含β -2微球蛋白大分子复合物在结节病血清中的高发。

Acta pathologica, microbiologica, et immunologica Scandinavica. Section C, Immunology Pub Date : 1983-02-01

A Falus, G Glikmann, S E Svehag

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引用次数: 0

摘要

在14例结节病患者中，有13例血清免疫复合物β -2-微球蛋白(β 2m)水平升高，可在3%聚乙二醇沉淀制备的免疫复合物富集馏分中检测到。用固相Clq分离的复合物中也含有β -2微球蛋白。结节病血清中游离β 2m的水平与健康供者血清中的浓度没有差异。

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High incidence of beta-2-microglobulin containing macromolecular complexes in sarcoidosis sera.

In thirteen out of fourteen sarcoidosis patients with elevated serum levels of immune complexes beta-2-microglobulin (beta 2m) was detected in immune complex-enriched fractions prepared by precipitation with 3% polyethylene glycol. Beta-2-microglobulin was also contained in complexes isolated by means of solid-phase Clq. The levels of free beta 2m in sarcoidosis sera did not differ from the concentrations in sera from healthy donors.

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Acta pathologica, microbiologica, et immunologica Scandinavica. Section C, Immunology

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