R F James, R Szumski, P G Gillett, J Shuster, P Gold
{"title":"妊娠期孕妇血浆HbF水平。","authors":"R F James, R Szumski, P G Gillett, J Shuster, P Gold","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Serial maternal serum hemoglobin F (HbF) levels were measured by radioimmunoassay in 23 normal pregnancies. The maternal HbF fraction remains within the normal range during the first trimester (mean + 2 S.D. = 0.15 + 0.13). After 15 weeks gestation, maternal HbF levels rise in some, but not all, pregnancies. In about 30% of the cases the HbF fraction remains within the range seen in adult men and non-pregnant women. Irregular rises in HbF were found in other pregnancies studied serially. The maternal HbF fraction may be an indicator of transplacental hemorrhage.</p>","PeriodicalId":79244,"journal":{"name":"Oncodevelopmental biology and medicine : the journal of the International Society for Oncodevelopmental Biology and Medicine","volume":"4 4","pages":"239-44"},"PeriodicalIF":0.0000,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Maternal plasma HbF levels in pregnancy.\",\"authors\":\"R F James, R Szumski, P G Gillett, J Shuster, P Gold\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Serial maternal serum hemoglobin F (HbF) levels were measured by radioimmunoassay in 23 normal pregnancies. The maternal HbF fraction remains within the normal range during the first trimester (mean + 2 S.D. = 0.15 + 0.13). After 15 weeks gestation, maternal HbF levels rise in some, but not all, pregnancies. In about 30% of the cases the HbF fraction remains within the range seen in adult men and non-pregnant women. Irregular rises in HbF were found in other pregnancies studied serially. The maternal HbF fraction may be an indicator of transplacental hemorrhage.</p>\",\"PeriodicalId\":79244,\"journal\":{\"name\":\"Oncodevelopmental biology and medicine : the journal of the International Society for Oncodevelopmental Biology and Medicine\",\"volume\":\"4 4\",\"pages\":\"239-44\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1983-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Oncodevelopmental biology and medicine : the journal of the International Society for Oncodevelopmental Biology and Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oncodevelopmental biology and medicine : the journal of the International Society for Oncodevelopmental Biology and Medicine","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Serial maternal serum hemoglobin F (HbF) levels were measured by radioimmunoassay in 23 normal pregnancies. The maternal HbF fraction remains within the normal range during the first trimester (mean + 2 S.D. = 0.15 + 0.13). After 15 weeks gestation, maternal HbF levels rise in some, but not all, pregnancies. In about 30% of the cases the HbF fraction remains within the range seen in adult men and non-pregnant women. Irregular rises in HbF were found in other pregnancies studied serially. The maternal HbF fraction may be an indicator of transplacental hemorrhage.