急性白血病和恶性淋巴瘤儿童水痘活疫苗的应用。

Biken journal Pub Date : 1984-09-01
Y Sato, T Miyano, K Kawauchi, M Yokoyama
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引用次数: 0

摘要

对7例急性白血病患儿和1例非霍奇金淋巴瘤患儿接种水痘活疫苗。4例急性白血病患儿在未中断抗癌药物治疗的情况下,血清转化无临床反应。这些儿童在接种疫苗后5至11个月没有水痘。4名接受缓解诱导化疗的儿童中有3名出现轻度至重度临床反应。结论水痘活疫苗在不中断抗癌药物治疗的急性白血病患儿中是有效的,但不适用于正在接受抗白血病药物缓解诱导化疗的白血病和淋巴瘤患儿。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Use of live varicella vaccine in children with acute leukemia and malignant lymphoma.

Live varicella vaccine was given to 7 children with acute leukemia and 1 child with non-Hodgkin's lymphoma. Seroconversion without any clinical reactions was observed in 4 children in remission from acute leukemia without interruption of anticancer medication. These children have been free from varicella for 5 to 11 months after vaccination. Mild to severe clinical reactions developed in 3 of 4 children who were receiving remission induction chemotherapy. It is concluded that live varicella vaccine is effective in children with acute leukemia without interrupting anticancer medication, but that it is not suitable for children with leukemia and lymphoma who are receiving remission induction chemotherapy with antileukemic agents.

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