{"title":"人类和实验性动脉粥样硬化病变中经转酰基化的胆固醇酯化","authors":"Y.H. Abdulla , C.C. Orton, C.W.M. Adams","doi":"10.1016/S0368-1319(68)80011-0","DOIUrl":null,"url":null,"abstract":"<div><p><em>In vitro</em> cholesterol esterification by either human or rabbit’s aorta in the presence of <em>β</em>-fatty acid-labelled lecithin appears to depend on a lecithin:cholesterol fatty acid (acyl) transferase. The activity of this enzyme increases in human fatty atherosclerotic lesions and in atherosclerotic aortas from cholesterol-fed rabbits. Activity decreases in fibrous and calcified human atherosclerotic lesions.</p></div>","PeriodicalId":78351,"journal":{"name":"Journal of atherosclerosis research","volume":"8 6","pages":"Pages 967-973"},"PeriodicalIF":0.0000,"publicationDate":"1968-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0368-1319(68)80011-0","citationCount":"58","resultStr":"{\"title\":\"Cholesterol esterification by transacylation in human and experimental atheromatous lesions\",\"authors\":\"Y.H. Abdulla , C.C. Orton, C.W.M. Adams\",\"doi\":\"10.1016/S0368-1319(68)80011-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p><em>In vitro</em> cholesterol esterification by either human or rabbit’s aorta in the presence of <em>β</em>-fatty acid-labelled lecithin appears to depend on a lecithin:cholesterol fatty acid (acyl) transferase. The activity of this enzyme increases in human fatty atherosclerotic lesions and in atherosclerotic aortas from cholesterol-fed rabbits. Activity decreases in fibrous and calcified human atherosclerotic lesions.</p></div>\",\"PeriodicalId\":78351,\"journal\":{\"name\":\"Journal of atherosclerosis research\",\"volume\":\"8 6\",\"pages\":\"Pages 967-973\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1968-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/S0368-1319(68)80011-0\",\"citationCount\":\"58\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of atherosclerosis research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0368131968800110\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of atherosclerosis research","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0368131968800110","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Cholesterol esterification by transacylation in human and experimental atheromatous lesions
In vitro cholesterol esterification by either human or rabbit’s aorta in the presence of β-fatty acid-labelled lecithin appears to depend on a lecithin:cholesterol fatty acid (acyl) transferase. The activity of this enzyme increases in human fatty atherosclerotic lesions and in atherosclerotic aortas from cholesterol-fed rabbits. Activity decreases in fibrous and calcified human atherosclerotic lesions.
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