Studies of optimal conditions for the measurement of circulating endogenous lipoprotein lipase activity

In 63 of 86 experiments there was a significantly greater release of free fatty acids when platelet-rich human plasma was incubated with coconut oil than when platelet-poor plasma was used. In 19 of 20 experiments fatty acid-poor albumin enhanced the lipolysis of coconut oil. The results of this study indicate that platelet-rich plasma and fatty acid-poor albumin should be used when endogenous plasma lipoprotein lipase activity is determined in vitro.