{"title":"未成熟猴子的冠状动脉","authors":"Z. Vlodaver, J. Medalie , H.N. Neufeld","doi":"10.1016/S0368-1319(68)80006-7","DOIUrl":null,"url":null,"abstract":"<div><p>A histological study of the structural changes in the coronary arteries of 53 unselected immature monkeys is presented.</p><p>Two species of Old World monkey—23 rhesus and 30 vervet monkeys were studied.</p><p>The development of intimai changes in these animals is similar to the degenerative and proliferative changes seen in human coronary arteries during early life.</p><p>The musculo-elastic layer found in man does not develop in young monkeys.</p><p>The intimai changes encountered in the immature captive monkeys in this study were apparently not related to the fat content of the diet, which was low in both groups, or to the level of serum cholesterol and phospholipids, which were within normal limits.</p><p>The possible relation between stress and physical activity and the development of intimai changes in the captive monkeys is stressed and the need for further studies to evaluate this problem is emphasized.</p></div>","PeriodicalId":78351,"journal":{"name":"Journal of atherosclerosis research","volume":"8 6","pages":"Pages 923-933"},"PeriodicalIF":0.0000,"publicationDate":"1968-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0368-1319(68)80006-7","citationCount":"5","resultStr":"{\"title\":\"Coronary arteries in immature monkeys\",\"authors\":\"Z. Vlodaver, J. Medalie , H.N. Neufeld\",\"doi\":\"10.1016/S0368-1319(68)80006-7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>A histological study of the structural changes in the coronary arteries of 53 unselected immature monkeys is presented.</p><p>Two species of Old World monkey—23 rhesus and 30 vervet monkeys were studied.</p><p>The development of intimai changes in these animals is similar to the degenerative and proliferative changes seen in human coronary arteries during early life.</p><p>The musculo-elastic layer found in man does not develop in young monkeys.</p><p>The intimai changes encountered in the immature captive monkeys in this study were apparently not related to the fat content of the diet, which was low in both groups, or to the level of serum cholesterol and phospholipids, which were within normal limits.</p><p>The possible relation between stress and physical activity and the development of intimai changes in the captive monkeys is stressed and the need for further studies to evaluate this problem is emphasized.</p></div>\",\"PeriodicalId\":78351,\"journal\":{\"name\":\"Journal of atherosclerosis research\",\"volume\":\"8 6\",\"pages\":\"Pages 923-933\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1968-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/S0368-1319(68)80006-7\",\"citationCount\":\"5\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of atherosclerosis research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0368131968800067\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of atherosclerosis research","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0368131968800067","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A histological study of the structural changes in the coronary arteries of 53 unselected immature monkeys is presented.
Two species of Old World monkey—23 rhesus and 30 vervet monkeys were studied.
The development of intimai changes in these animals is similar to the degenerative and proliferative changes seen in human coronary arteries during early life.
The musculo-elastic layer found in man does not develop in young monkeys.
The intimai changes encountered in the immature captive monkeys in this study were apparently not related to the fat content of the diet, which was low in both groups, or to the level of serum cholesterol and phospholipids, which were within normal limits.
The possible relation between stress and physical activity and the development of intimai changes in the captive monkeys is stressed and the need for further studies to evaluate this problem is emphasized.
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