制定牙科材料和产品的毒性评估程序。2筛选全身毒性

IF 3.9 3区医学 Q2 ENGINEERING, BIOMEDICAL

Journal of biomedical materials research. Part A Pub Date : 1974-01-01 DOI:10.1002/jbm.820080104

W. H. Lawrence, M. Malik, J. Autian

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引用次数: 33

摘要

对各种类型化合物的一系列全身毒性试验提出了说明性数据，并讨论了它们作为牙科化合物和产品的潜在筛选试验的相关性。在开发和销售一种新的牙科材料时，重要的是不仅要确保患者的安全，而且要确保牙医、牙科助理和经常处理和使用该产品的实验室工作人员的安全。数据提出了一些市售牙科产品以及各种化学实体，这是由一种或多种方法所述的测试。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Development of a toxicity evaluation program for dental materials and products. II. Screening for systemic toxicity

A series of systemic toxicity tests for various types of compounds are presented with illustrative data and discussed in regard to their relevance as potential screening tests for dental compounds and products. In developing and marketing a new dental material, it is important not only to ensure safety for the patient but also for the dentist, dental assistant, and laboratory worker who routinely handles and uses the product. Data are presented on a number of commercially available dental products as well as various chemical entities, which were tested by one or more of the methods described.

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来源期刊

Journal of biomedical materials research. Part A 工程技术-材料科学：生物材料

CiteScore

10.40

自引率

2.00%

发文量

135

审稿时长

3.6 months

期刊介绍： The Journal of Biomedical Materials Research Part A is an international, interdisciplinary, English-language publication of original contributions concerning studies of the preparation, performance, and evaluation of biomaterials; the chemical, physical, toxicological, and mechanical behavior of materials in physiological environments; and the response of blood and tissues to biomaterials. The Journal publishes peer-reviewed articles on all relevant biomaterial topics including the science and technology of alloys,polymers, ceramics, and reprocessed animal and human tissues in surgery,dentistry, artificial organs, and other medical devices. The Journal also publishes articles in interdisciplinary areas such as tissue engineering and controlled release technology where biomaterials play a significant role in the performance of the medical device. The Journal of Biomedical Materials Research is the official journal of the Society for Biomaterials (USA), the Japanese Society for Biomaterials, the Australasian Society for Biomaterials, and the Korean Society for Biomaterials. Articles are welcomed from all scientists. Membership in the Society for Biomaterials is not a prerequisite for submission.