药用植物物质的分子药理学研究。2单萜衍生物对乙酰胆碱酯酶的体外抑制作用[j]。

L Gracza
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引用次数: 22

摘要

具有解痉活性的单萜衍生物体外抑制乙酰胆碱酯酶(ACHE, EC 3.1.1.7)呈剂量依赖性。中位抑制浓度范围在10(-4)M和10(-2)M之间。本研究的意义可能是单萜衍生物在消化道紊乱中的作用的可能解释。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Molecular pharmacological investigation of medicinal plant substances. II. Inhibition of acetylcholinesterase by monoterpene derivatives in vitro].

Monoterpene derivatives with spasmolytic activity inhibited acetylcholinesterase (ACHE, EC 3.1.1.7) in a dose dependent manner in vitro. The median inhibitory concentrations ranges between 10(-4) M and 10(-2) M. A significance of our finding may be the possible explanation of effects of monoterpene derivatives seen in distony of digestive tract.

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