{"title":"药用植物物质的分子药理学研究。2单萜衍生物对乙酰胆碱酯酶的体外抑制作用[j]。","authors":"L Gracza","doi":"10.1515/znc-1985-3-401","DOIUrl":null,"url":null,"abstract":"<p><p>Monoterpene derivatives with spasmolytic activity inhibited acetylcholinesterase (ACHE, EC 3.1.1.7) in a dose dependent manner in vitro. The median inhibitory concentrations ranges between 10(-4) M and 10(-2) M. A significance of our finding may be the possible explanation of effects of monoterpene derivatives seen in distony of digestive tract.</p>","PeriodicalId":23914,"journal":{"name":"Zeitschrift fur Naturforschung. Section C, Biosciences","volume":"40 3-4","pages":"151-3"},"PeriodicalIF":0.0000,"publicationDate":"1985-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1515/znc-1985-3-401","citationCount":"22","resultStr":"{\"title\":\"[Molecular pharmacological investigation of medicinal plant substances. II. Inhibition of acetylcholinesterase by monoterpene derivatives in vitro].\",\"authors\":\"L Gracza\",\"doi\":\"10.1515/znc-1985-3-401\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Monoterpene derivatives with spasmolytic activity inhibited acetylcholinesterase (ACHE, EC 3.1.1.7) in a dose dependent manner in vitro. The median inhibitory concentrations ranges between 10(-4) M and 10(-2) M. A significance of our finding may be the possible explanation of effects of monoterpene derivatives seen in distony of digestive tract.</p>\",\"PeriodicalId\":23914,\"journal\":{\"name\":\"Zeitschrift fur Naturforschung. Section C, Biosciences\",\"volume\":\"40 3-4\",\"pages\":\"151-3\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1985-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1515/znc-1985-3-401\",\"citationCount\":\"22\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Zeitschrift fur Naturforschung. Section C, Biosciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1515/znc-1985-3-401\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zeitschrift fur Naturforschung. Section C, Biosciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1515/znc-1985-3-401","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[Molecular pharmacological investigation of medicinal plant substances. II. Inhibition of acetylcholinesterase by monoterpene derivatives in vitro].
Monoterpene derivatives with spasmolytic activity inhibited acetylcholinesterase (ACHE, EC 3.1.1.7) in a dose dependent manner in vitro. The median inhibitory concentrations ranges between 10(-4) M and 10(-2) M. A significance of our finding may be the possible explanation of effects of monoterpene derivatives seen in distony of digestive tract.