辐照无牙患者的口腔表现

Carl-Henrik Bernhoft , Nils Skaug
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引用次数: 39

摘要

11例口腔或口咽恶性肿瘤无牙患者(平均年龄71.2岁)在接受头颈部肿瘤杀伤辐射剂量(26.4-74 Gy)之前、期间和之后进行了临床和微生物学检查。研究了监督口腔卫生计划和唾液替代品(Va-OraLube)的效果。观察期内存活的9例患者均出现与放射线增加有关的口干和粘膜炎增加。未见放射性坏死或口腔感染。患者在整个观察期间都戴着假牙,并倾向于使用唾液替代品。初始嗜酸菌数量较多,白色念珠菌数量较少,肠道细菌出现频率高于正常。引入卫生项目后,微生物减少了。结论:在头颈部无牙区行肿瘤放射治疗的患者中,周密的放疗计划、放疗前口腔检查、义齿控制和指导以及有效的口腔卫生规划是减少口腔并发症的关键。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Oral findings in irradiated edentulous patients

11 edentulous patients (mean age 71.2 years) with oral or oropharyngeal malignancies were examined clinically and microbiologi-cally before, during, and after receiving tumoricidal radiation doses (26.4–74 Gy) towards the head and neck regions. The effect of a supervised oral hygiene program and a saliva substitute (Va-OraLube) was studied. The 9 patients who survived the observation period, showed increased xerostomia and mucositis related to increased radiation. Radionecrosis or oral infections were not observed. The patients wore their dentures throughout the observation period and preferred to use the saliva substitute. The initial number of acidophilic bacteria was high, Candida albicans were present in low numbers and enteric bacteria occurred more frequently than normally. There was a reduction of micro-organisms after introduction of the hygiene program. It is concluded that careful planning of the radiotherapy, preradiation oral examination, denture control and instruction and an effective oral hygiene program are essential for the reduction of oral complications in edentulous patients receiving tumoricidal radiotherapy to the head and neck regions.

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