自闭症儿童群体中的脆性X综合征

HARRY H. WRIGHT M.D., M.B.A., S ROBERT YOUNG Ph.D., JANICE G. EDWARDS M.S., RUTH K. ABRAMSON Ph.D., JOANN DUNCAN M.A., M.S.W.
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引用次数: 24

摘要

脆性X综合征,最近被描述为一种与X相关的智力迟钝,据报道与婴儿自闭症有关。在对40名符合DSM-III婴儿自闭症标准的儿童的染色体分析中,发现了大量可能的常染色体脆性位点,但只有一名儿童的脆性X基因呈阳性。作者得出结论,脆性X综合征与婴儿自闭症的关联可能比之前认为的要少。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Fragile X Syndrome in a Population of Autistic Children

Fragile X syndrome, a recently described form of X-linked mental retardation, has been reported to be associated with infantile autism. In chromosomal analysis of 40 children who met DSM-III criteria for infantile autism, a large number of possible autosomal fragile sites were noted, but only one child was positive for fragile X. The authors concluded that the association of fragile X syndrome and infantile autism may be less frequent than previously thought.

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