Silvia Victoria Prodescu, Paul Filip Curcă, Călin Petru Tătaru, Cătălina Ioana Tătaru
{"title":"高散光（≥2.00 D）的StreamLight Trans-PRK的早期视力、屈光和散光矢量结果。","authors":"Silvia Victoria Prodescu, Paul Filip Curcă, Călin Petru Tătaru, Cătălina Ioana Tătaru","doi":"10.22336/rjo.2026.32","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To report the early refractive, visual, and astigmatic-vector outcomes of single-step StreamLight™ transepithelial photorefractive keratectomy (Trans-PRK) on the WaveLight EX500 platform in eyes with high preoperative astigmatism (≥ 2.00 dioptres, D).</p><p><strong>Methods: </strong>Single-centre cohort study of 171 consecutive eyes of 107 patients (mean age 27.87 ± 6.56 years; 37.4% female) treated by a single surgeon. Astigmatic outcomes were analyzed by the Alpins method at the corneal plane. A subset of 57 eyes with a mean follow-up of 10.3 ± 7.4 months underwent stability sub-analysis.</p><p><strong>Results: </strong>Mean preoperative cylinder was 3.29 ± 0.81 D and mean spherical equivalent (SE) was -2.73 ± 2.56 D. At one month, mean UDVA was 0.05 ± 0.09 logMAR, mean residual cylinder was 0.65 ± 0.44 D, and mean SE was -0.22 ± 0.47 D. SE was within ±0.50 D of intended in 71.3% of eyes; cylinder was ≤ 0.50 D in 53.2%. Mean efficacy and safety indices were 1.04 ± 0.22 and 1.10 ± 0.22, respectively, with no eye losing two or more lines of CDVA. Vector analysis yielded a correction index of 1.09 ± 0.16, an index of success of 0.21 ± 0.14, and 99% of eyes within ±15° of the intended axis. Stability sub-analysis showed minimal change in SE and an unchanged cylinder between 1 month and a mean follow-up of 10.3 ± 7.4 months (SE -0.14 to -0.07 D).</p><p><strong>Discussion: </strong>Trans-PRK delivered good early visual, refractive, and astigmatic vector outcomes. Axis precision was high with a mean angle of error of -0.81 ± 5.32°, 80% of eyes within ±5°, and 99% within ±15° of the intended axis. Interpretation of vectorial results is subject to the specificity of the 1-month post-Trans-PRK central epithelial thickness (CET decreases in the first week, returns to baseline at 1 month, and progressively increases up to 6 months).</p><p><strong>Conclusions: </strong>Single-step StreamLight™ Trans-PRK on the WaveLight EX500 platform achieves favorable early refractive, visual, and vector-analytic outcomes in eyes with high preoperative astigmatism, with corneal-plane vector parameters that compare favorably with those reported in the published Trans-PRK literature.</p>","PeriodicalId":94355,"journal":{"name":"Romanian journal of ophthalmology","volume":"70 2","pages":"233-248"},"PeriodicalIF":0.0000,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13453120/pdf/","citationCount":"0","resultStr":"{\"title\":\"Early Visual, Refractive, and Astigmatism Vector Outcomes of StreamLight Trans-PRK for High Astigmatism (≥ 2.00 D).\",\"authors\":\"Silvia Victoria Prodescu, Paul Filip Curcă, Călin Petru Tătaru, Cătălina Ioana Tătaru\",\"doi\":\"10.22336/rjo.2026.32\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To report the early refractive, visual, and astigmatic-vector outcomes of single-step StreamLight™ transepithelial photorefractive keratectomy (Trans-PRK) on the WaveLight EX500 platform in eyes with high preoperative astigmatism (≥ 2.00 dioptres, D).</p><p><strong>Methods: </strong>Single-centre cohort study of 171 consecutive eyes of 107 patients (mean age 27.87 ± 6.56 years; 37.4% female) treated by a single surgeon. Astigmatic outcomes were analyzed by the Alpins method at the corneal plane. A subset of 57 eyes with a mean follow-up of 10.3 ± 7.4 months underwent stability sub-analysis.</p><p><strong>Results: </strong>Mean preoperative cylinder was 3.29 ± 0.81 D and mean spherical equivalent (SE) was -2.73 ± 2.56 D. At one month, mean UDVA was 0.05 ± 0.09 logMAR, mean residual cylinder was 0.65 ± 0.44 D, and mean SE was -0.22 ± 0.47 D. SE was within ±0.50 D of intended in 71.3% of eyes; cylinder was ≤ 0.50 D in 53.2%. Mean efficacy and safety indices were 1.04 ± 0.22 and 1.10 ± 0.22, respectively, with no eye losing two or more lines of CDVA. Vector analysis yielded a correction index of 1.09 ± 0.16, an index of success of 0.21 ± 0.14, and 99% of eyes within ±15° of the intended axis. Stability sub-analysis showed minimal change in SE and an unchanged cylinder between 1 month and a mean follow-up of 10.3 ± 7.4 months (SE -0.14 to -0.07 D).</p><p><strong>Discussion: </strong>Trans-PRK delivered good early visual, refractive, and astigmatic vector outcomes. Axis precision was high with a mean angle of error of -0.81 ± 5.32°, 80% of eyes within ±5°, and 99% within ±15° of the intended axis. Interpretation of vectorial results is subject to the specificity of the 1-month post-Trans-PRK central epithelial thickness (CET decreases in the first week, returns to baseline at 1 month, and progressively increases up to 6 months).</p><p><strong>Conclusions: </strong>Single-step StreamLight™ Trans-PRK on the WaveLight EX500 platform achieves favorable early refractive, visual, and vector-analytic outcomes in eyes with high preoperative astigmatism, with corneal-plane vector parameters that compare favorably with those reported in the published Trans-PRK literature.</p>\",\"PeriodicalId\":94355,\"journal\":{\"name\":\"Romanian journal of ophthalmology\",\"volume\":\"70 2\",\"pages\":\"233-248\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2026-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13453120/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Romanian journal of ophthalmology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.22336/rjo.2026.32\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Romanian journal of ophthalmology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22336/rjo.2026.32","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Early Visual, Refractive, and Astigmatism Vector Outcomes of StreamLight Trans-PRK for High Astigmatism (≥ 2.00 D).
Objective: To report the early refractive, visual, and astigmatic-vector outcomes of single-step StreamLight™ transepithelial photorefractive keratectomy (Trans-PRK) on the WaveLight EX500 platform in eyes with high preoperative astigmatism (≥ 2.00 dioptres, D).
Methods: Single-centre cohort study of 171 consecutive eyes of 107 patients (mean age 27.87 ± 6.56 years; 37.4% female) treated by a single surgeon. Astigmatic outcomes were analyzed by the Alpins method at the corneal plane. A subset of 57 eyes with a mean follow-up of 10.3 ± 7.4 months underwent stability sub-analysis.
Results: Mean preoperative cylinder was 3.29 ± 0.81 D and mean spherical equivalent (SE) was -2.73 ± 2.56 D. At one month, mean UDVA was 0.05 ± 0.09 logMAR, mean residual cylinder was 0.65 ± 0.44 D, and mean SE was -0.22 ± 0.47 D. SE was within ±0.50 D of intended in 71.3% of eyes; cylinder was ≤ 0.50 D in 53.2%. Mean efficacy and safety indices were 1.04 ± 0.22 and 1.10 ± 0.22, respectively, with no eye losing two or more lines of CDVA. Vector analysis yielded a correction index of 1.09 ± 0.16, an index of success of 0.21 ± 0.14, and 99% of eyes within ±15° of the intended axis. Stability sub-analysis showed minimal change in SE and an unchanged cylinder between 1 month and a mean follow-up of 10.3 ± 7.4 months (SE -0.14 to -0.07 D).
Discussion: Trans-PRK delivered good early visual, refractive, and astigmatic vector outcomes. Axis precision was high with a mean angle of error of -0.81 ± 5.32°, 80% of eyes within ±5°, and 99% within ±15° of the intended axis. Interpretation of vectorial results is subject to the specificity of the 1-month post-Trans-PRK central epithelial thickness (CET decreases in the first week, returns to baseline at 1 month, and progressively increases up to 6 months).
Conclusions: Single-step StreamLight™ Trans-PRK on the WaveLight EX500 platform achieves favorable early refractive, visual, and vector-analytic outcomes in eyes with high preoperative astigmatism, with corneal-plane vector parameters that compare favorably with those reported in the published Trans-PRK literature.
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