M. Bernaola, A. Gago, A. Umpiérrez, E. López-Soberón, N.G. Kounis
{"title":"抗生素会引起急性冠状动脉综合征吗?术后对阿莫西林过敏引起的Kounis综合征:一个临床病例","authors":"M. Bernaola, A. Gago, A. Umpiérrez, E. López-Soberón, N.G. Kounis","doi":"10.1016/j.redar.2026.502035","DOIUrl":null,"url":null,"abstract":"<div><div>Kounis syndrome (KS) is an acute coronary syndrome triggered by mast cell degranulation in response to allergic or hypersensitivity reactions. Drug-induced KS, particularly due to antibiotics like amoxicillin, represents a severe and potentially life-threatening condition. This review aims to analyze the pathophysiology, clinical manifestations, diagnostic approaches, and management strategies of KS induced by amoxicillin allergy, with a focus on recent literature and emerging therapeutic insights.</div></div>","PeriodicalId":46479,"journal":{"name":"Revista Espanola de Anestesiologia y Reanimacion","volume":"73 7","pages":"Article 502035"},"PeriodicalIF":1.3000,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"¿Puede un antibiótico provocar un síndrome coronario agudo? Síndrome de Kounis inducido por alergia intraoperatoria a amoxicilina: un caso clínico\",\"authors\":\"M. Bernaola, A. Gago, A. Umpiérrez, E. López-Soberón, N.G. Kounis\",\"doi\":\"10.1016/j.redar.2026.502035\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Kounis syndrome (KS) is an acute coronary syndrome triggered by mast cell degranulation in response to allergic or hypersensitivity reactions. Drug-induced KS, particularly due to antibiotics like amoxicillin, represents a severe and potentially life-threatening condition. This review aims to analyze the pathophysiology, clinical manifestations, diagnostic approaches, and management strategies of KS induced by amoxicillin allergy, with a focus on recent literature and emerging therapeutic insights.</div></div>\",\"PeriodicalId\":46479,\"journal\":{\"name\":\"Revista Espanola de Anestesiologia y Reanimacion\",\"volume\":\"73 7\",\"pages\":\"Article 502035\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2026-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista Espanola de Anestesiologia y Reanimacion\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0034935626000010\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2026/2/18 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"ANESTHESIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Espanola de Anestesiologia y Reanimacion","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0034935626000010","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/2/18 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"ANESTHESIOLOGY","Score":null,"Total":0}
¿Puede un antibiótico provocar un síndrome coronario agudo? Síndrome de Kounis inducido por alergia intraoperatoria a amoxicilina: un caso clínico
Kounis syndrome (KS) is an acute coronary syndrome triggered by mast cell degranulation in response to allergic or hypersensitivity reactions. Drug-induced KS, particularly due to antibiotics like amoxicillin, represents a severe and potentially life-threatening condition. This review aims to analyze the pathophysiology, clinical manifestations, diagnostic approaches, and management strategies of KS induced by amoxicillin allergy, with a focus on recent literature and emerging therapeutic insights.