利用合成受体修复生物毒性

IF 11.1 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

ACS Central Science Pub Date : 2026-05-27 Epub Date: 2026-05-11 DOI:10.1021/acscentsci.6c00706

Richard J. Hooley,

引用次数: 0

摘要

水溶性合成受体选择性结合细胞中的α-突触核蛋白，破坏朊病毒样聚集体的形成，修复聚集体的毒性作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Remediating Biotoxicity with Synthetic Receptors

Water-soluble synthetic receptors selectively bind α-synuclein in cells and disrupt the formation of prion-like aggregates, remediating the toxic effects of aggregation.

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来源期刊

ACS Central Science Chemical Engineering-General Chemical Engineering

CiteScore

25.50

自引率

0.50%

发文量

194

审稿时长

10 weeks

期刊介绍： ACS Central Science publishes significant primary reports on research in chemistry and allied fields where chemical approaches are pivotal. As the first fully open-access journal by the American Chemical Society, it covers compelling and important contributions to the broad chemistry and scientific community. "Central science," a term popularized nearly 40 years ago, emphasizes chemistry's central role in connecting physical and life sciences, and fundamental sciences with applied disciplines like medicine and engineering. The journal focuses on exceptional quality articles, addressing advances in fundamental chemistry and interdisciplinary research.