氮表面放电等离子体处理水凝胶的杀菌效果及机理研究

IF 3.2 3区物理与天体物理 Q2 PHYSICS, APPLIED

Journal of Physics D: Applied Physics Pub Date : 2025-12-08 DOI:10.1088/1361-6463/ae292b

Jishen Zhang, Xian Wang, Jinkun Chen, Mengke Li, Qiuyi Yue, Xinwei Lu, Weiji Yang, Zifeng Wang, Hao Zhang, Li Guo, Dingxin Liu, Jianbao Zheng, Mingzhe Rong

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引用次数: 0

摘要

作为等离子体生成的活性氧和活性氮（RONS）的新型载体，等离子体处理水凝胶（PTHs）具有广泛的生物医学应用。调节PTHs中的关键活性物质对于优化生物医学效果至关重要。本文主要研究了表面介质阻挡放电放电气体中n2 / o2比对等离子体处理AVC水凝胶（PTH AVC）杀菌效果的影响及其与ron生成的关系。结果表明，当o2含量为70%时，PTH AVC的杀菌效果最好，ONOO−aq /ONOOH aq浓度最高，说明ONOO−aq /ONOOH aq可能在PTH AVC的杀菌效果中起关键作用。本研究为调控PTH AVC的生物活性提供了新的策略，并为其杀菌机制提供了有价值的见解。

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Study on the bactericidal effect and its mechanism of nitrox surface discharge plasma-treated hydrogel

Abstract As novel carriers of plasma-generated reactive oxygen and nitrogen species (RONS), plasma-treated hydrogels (PTHs) have broad biomedical applications. Regulating the key reactive species in PTHs is crucial for optimal biomedical effects. This study focuses on how N 2 /O 2 ratios in discharge gas of surface dielectric barrier discharge affect RONS generation and its correlation with the bactericidal effect plasma-treated AVC hydrogel (PTH AVC ). It was found that PTH AVC achieved the best bactericidal effect and contained the highest concentration of ONOO − aq /ONOOH aq when the O 2 content was 70%, indicating that ONOO − aq /ONOOH aq may play a key role in the bactericidal effect of PTH AVC . This study provides a new strategy to regulate the biological activity of PTH AVC and valuable insights into its bactericidal mechanism.

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来源期刊

Journal of Physics D: Applied Physics 物理-物理：应用

CiteScore

6.80

自引率

8.80%

发文量

835

审稿时长

2.1 months

期刊介绍： This journal is concerned with all aspects of applied physics research, from biophysics, magnetism, plasmas and semiconductors to the structure and properties of matter.