14岁泌尿系结核一例:诊断与手术处理。

R Mena, R Gander, N Mendoza, A Soriano, M Asensio
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引用次数: 0

摘要

泌尿生殖系统结核(UG-TB)占肺外结核(EPTB)病例的30-40%,在儿科年龄极为罕见。它通常在晚期被诊断出来,其治疗主要需要抗结核治疗结合手术。临床病例:14岁患者,既往无肺部疾病史,复发性尿路感染(无菌脓尿),慢性下尿路症状。超声显示右侧肾积水,CT扫描显示椎体病变,诊断为结核。经抗胆碱能药物、耻骨上置管和透明质酸注入联合治疗后,泌尿系统症状得到改善。进一步的研究显示右肾萎缩,实质钙化和多处输尿管狭窄。由于全肾受累和功能,右肾输尿管切除术在腹腔镜下进行,无并发症。完成抗结核治疗后,耻骨上导管被取出,患者被转移到清洁间歇置管(CIC)。目前,在间歇置管下,临床病程良好,无感染发作,并保持对孤立剩余肾脏的定期随访。结论:出现无菌脓尿的复发性尿路感染患者必须怀疑UG-TB。尽管与这种病理相关的强烈疤痕,腹腔镜方法是安全可行的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A rare case of urinary tuberculosis in a 14-year-old: Diagnosis and surgical management.

Introduction: Urogenital tuberculosis (UG-TB) accounts for 30-40% of extrapulmonary TB (EPTB) cases and is extremely rare in the pediatric age. It is usually diagnosed in advanced stages, and its treatment mostly requires antitubercular therapy combined with surgery.

Clinical case: 14-year-old patient with no previous history of lung disease, who presented recurrent UTIs (sterile pyuria) and chronic lower urinary tract symptoms. On ultrasound right hydronephrosis was seen, and a CT scan revealed vertebral lesions that led to the diagnosis of TB. Urinary symptoms improved after combined treatment with anticholinergics, suprapubic catheter placement and hyaluronic acid instillations. Additional studies showed right renal atrophy, parenchymatous calcifications and multiple ureteral stenoses. Due to global renal involvement and afunctionality, right nephroureterectomy was performed laparoscopically, without complications. Following completion of antituberculous therapy, the suprapubic catheter was removed and the patient was transitioned to clean intermittent catheterization (CIC). At present, the clinical course is favorable under intermittent catheterization, with no infectious episodes, and regular follow-up of the solitary remaining kidney is maintained.

Conclusions: UG-TB must be suspected in patients with recurrent UTIs who present with sterile pyuria. Laparoscopic approach is safe and feasible in spite of the intense scarring associated with this pathology.

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