利用体外透射光谱技术评价有色防晒霜对蓝光的防护作用。

IF 2.2 4区 医学 Q2 DERMATOLOGY
Hawasatu Dumbuya, Katharine Podimatis, Pearl Grimes
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引用次数: 0

摘要

背景/用途:可见光光谱中的蓝光成分,波长在400-500 nm之间,具体为415 - 455nm,被称为高能可见光(HEV),具有最大的光生物学能力,包括生物效应和皮肤效应。目前,尚无评估防晒霜对戊肝病毒防护作用的监管指南。在这项研究中,我们利用体外透射光谱技术评估了不同颜色的防晒霜在蓝光照射后的hev阻断潜力。方法:我们比较了各种商用着色防晒霜配方,其SPF值从30到50不等,不同的紫外线过滤系统,抗氧化剂类型和氧化铁(FeO)浓度,以解释不同的色调。使用OL756光谱辐射计,在太阳模拟器蓝光照射(200 J/cm2)前后,测量PMMA板上每种防晒霜的HEV (415- 455nm)透射率。计算辐照前后各制剂的hev阻断电位百分比。结果:总体而言,与含有无机滤光剂氧化锌和二氧化钛的深色有机防晒霜或混合防晒霜相比,含有FeO和无机滤光剂的防晒霜显示出更高的HEV吸收谱和阻挡潜力。与先前的报道一致,HEV吸光度和阻断电位也与FeO水平相关。结论:这项研究的结果表明,根据配方的不同,商业化的有色防晒霜表现出不同程度的蓝光保护。考虑到有色防晒霜相对较新,加上缺乏监管标准,有必要进行更多的研究,开发方法来衡量产品对可见光/蓝光暴露的保护功效。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluation of Tinted Sunscreens Protection Against Blue Light Using Transmittance Spectroscopy In Vitro Technique.

Background/purpose: Blue light component of visible light spectrum, between the wavelengths of 400-500 nm, specifically from 415 to 455 nm, known as high energy visible (HEV) light, has the greatest photobiological capability, including biological and cutaneous effects. Currently, there are no regulatory guidelines for assessing sunscreens protection against HEV. In this study, we evaluated the HEV-blocking potential of various tinted sunscreens after blue light irradiation using transmittance spectroscopy in vitro technique.

Methods: We compared various commercialized tinted sunscreen formulations with SPF levels ranging from 30 to 50, varying UV filter systems, antioxidant types, and iron oxide (FeO) concentrations to account for different shades. HEV (415-455 nm) transmittance for each sunscreen applied on PMMA plates was measured using an OL756 spectroradiometer, before and after blue light irradiation (200 J/cm2) with solar simulator. The HEV-blocking potential percentage of each formulation was calculated before and after irradiation.

Results: Overall, sunscreens formulated with FeO and both inorganic filters, zinc oxide and titanium dioxide, demonstrated higher HEV absorbance profiles and blocking potential than darker-tinted organic sunscreens or hybrid, where one inorganic UV filter was present. Consistent with prior reports, the HEV absorbance and blocking potential also correlated with the FeO levels.

Conclusion: This study's findings suggest that depending on their formulations, commercialized tinted sunscreens exhibit different levels of blue light protection. Given the relative newness of tinted sunscreens, plus a lack of regulatory standards, there is a need for more research developing methods to measure protection efficacy of products against visible/blue light exposure.

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来源期刊
CiteScore
4.40
自引率
7.70%
发文量
85
审稿时长
6-12 weeks
期刊介绍: The journal is a forum for new information about the direct and distant effects of electromagnetic radiation (ultraviolet, visible and infrared) mediated through skin. The divisions of the editorial board reflect areas of specific interest: aging, carcinogenesis, immunology, instrumentation and optics, lasers, photodynamic therapy, photosensitivity, pigmentation and therapy. Photodermatology, Photoimmunology & Photomedicine includes original articles, reviews, communications and editorials. Original articles may include the investigation of experimental or pathological processes in humans or animals in vivo or the investigation of radiation effects in cells or tissues in vitro. Methodology need have no limitation; rather, it should be appropriate to the question addressed.
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