Duo Wai-Chi Wong , James Chung-Wai Cheung , Lucci Lugee Liyeung , Esther Man-Wai Chow , Winson Chiu-Chun Lee , Wenxin Niu , Ming Ni
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Finite element (FE) analysis is an increasingly critical <em>in silico</em> tool for optimizing implant designs and comparing fixation constructs, yet the technical modelling strategies and limitations specific to calcaneal fracture biomechanics have not been systematically mapped.</div></div><div><h3>Technology</h3><div>The FE modelling pipeline comprises sequential technical domains: (1) medical image-based geometry reconstruction and mesh generation; (2) material assignment (elastic modulus, Poisson's ratio, constitutive laws for bone, cartilage, and ligaments); (3) virtual fracture creation (gap width specification, Sanders classification implementation); (4) implant insertion (plate/screw/nail geometry, contact definition); (5) boundary conditions (standing/gait loading protocols, constraint schemes, muscle force incorporation); (6) solver configuration (static/quasi-static analysis); and (7) outcome extraction (von Mises stress, displacement, construct stiffness, micromotion metrics, etc.). This systematic scoping review followed JBI methodology and PRISMA-ScR guidelines to identify FE studies from PubMed, Web of Science, Scopus, and IEEE Xplore. Methodological quality was evaluated using the MQSSFE instrument for computational orthopaedic models.</div></div><div><h3>Results</h3><div>Twenty-three studies were included, predominantly using single-subject CT models with artificially created Sanders type II–III intra-articular fractures. Most employed calcaneus-only geometries, linear elastic isotropic bone properties, tetrahedral meshes, and quasi-static stance loading. Locking plates, hybrid plate–screw constructs, screw-only MIF, and intramedullary nails were compared via stress distribution and construct stiffness. Several studies introduced topology-optimized plates and micromotion-based fracture gap metrics, demonstrating that MIF with supplementary percutaneous screws can achieve biomechanical stability comparable to ORIF. However, verification (mesh convergence) and validation procedures were inconsistently reported, dynamic loading and multi-patient cohorts were rare, and interfragmentary strain–based healing criteria were largely absent. This delineation of the current technical design space highlights priorities for more physiologically realistic and methodologically robust <em>in silico</em> studies.</div></div>","PeriodicalId":100180,"journal":{"name":"Biomedical Technology","volume":"13 ","pages":"Article 100133"},"PeriodicalIF":0.0000,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Progress of computational biomechanical modelling for calcaneal fracture fixation\",\"authors\":\"Duo Wai-Chi Wong , James Chung-Wai Cheung , Lucci Lugee Liyeung , Esther Man-Wai Chow , Winson Chiu-Chun Lee , Wenxin Niu , Ming Ni\",\"doi\":\"10.1016/j.bmt.2026.100133\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>Calcaneal fractures are among the most disabling and costly orthopaedic injuries, frequently requiring surgical fixation via open reduction and internal fixation (ORIF) or minimally invasive fixation (MIF). Finite element (FE) analysis is an increasingly critical <em>in silico</em> tool for optimizing implant designs and comparing fixation constructs, yet the technical modelling strategies and limitations specific to calcaneal fracture biomechanics have not been systematically mapped.</div></div><div><h3>Technology</h3><div>The FE modelling pipeline comprises sequential technical domains: (1) medical image-based geometry reconstruction and mesh generation; (2) material assignment (elastic modulus, Poisson's ratio, constitutive laws for bone, cartilage, and ligaments); (3) virtual fracture creation (gap width specification, Sanders classification implementation); (4) implant insertion (plate/screw/nail geometry, contact definition); (5) boundary conditions (standing/gait loading protocols, constraint schemes, muscle force incorporation); (6) solver configuration (static/quasi-static analysis); and (7) outcome extraction (von Mises stress, displacement, construct stiffness, micromotion metrics, etc.). 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引用次数: 0
摘要
跟骨骨折是最致残性和最昂贵的骨科损伤之一,通常需要通过切开复位内固定(ORIF)或微创固定(MIF)进行手术固定。有限元(FE)分析在优化植入物设计和比较固定结构方面越来越重要,但与跟骨骨折生物力学相关的技术建模策略和局限性尚未得到系统的描述。有限元建模流程包括以下几个技术领域:(1)基于医学图像的几何重构和网格生成;(2)材料分配(弹性模量、泊松比、骨、软骨和韧带的本构律);(3)虚拟裂缝创建(间隙宽度规范,Sanders分类实现);(4)植入物置入(钢板/螺钉/钉的几何形状、接触定义);(5)边界条件(站立/步态加载协议、约束方案、肌力整合);(6)求解器配置(静态/准静态分析);(7)结果提取(von Mises应力、位移、结构刚度、微动指标等)。该系统的范围审查遵循JBI方法和PRISMA-ScR指南,从PubMed、Web of Science、Scopus和IEEE explore中确定FE研究。使用计算骨科模型的MQSSFE仪器评估方法学质量。结果纳入23项研究,主要使用人工制造Sanders II-III型关节内骨折的单受试者CT模型。大多数采用跟骨几何,线弹性各向同性骨特性,四面体网格和准静态姿态加载。通过应力分布和结构刚度对锁定钢板、混合钢板-螺钉结构、仅螺钉MIF和髓内钉进行比较。一些研究介绍了拓扑优化钢板和基于微运动的骨折间隙指标,表明MIF与补充经皮螺钉可以达到与ORIF相当的生物力学稳定性。然而,验证(网格收敛)和验证程序的报道不一致,动态加载和多患者队列很少,并且大部分缺乏基于碎片间应变的愈合标准。这种对当前技术设计空间的描述强调了在硅研究中更加生理现实和方法稳健的优先事项。
Progress of computational biomechanical modelling for calcaneal fracture fixation
Background
Calcaneal fractures are among the most disabling and costly orthopaedic injuries, frequently requiring surgical fixation via open reduction and internal fixation (ORIF) or minimally invasive fixation (MIF). Finite element (FE) analysis is an increasingly critical in silico tool for optimizing implant designs and comparing fixation constructs, yet the technical modelling strategies and limitations specific to calcaneal fracture biomechanics have not been systematically mapped.
Technology
The FE modelling pipeline comprises sequential technical domains: (1) medical image-based geometry reconstruction and mesh generation; (2) material assignment (elastic modulus, Poisson's ratio, constitutive laws for bone, cartilage, and ligaments); (3) virtual fracture creation (gap width specification, Sanders classification implementation); (4) implant insertion (plate/screw/nail geometry, contact definition); (5) boundary conditions (standing/gait loading protocols, constraint schemes, muscle force incorporation); (6) solver configuration (static/quasi-static analysis); and (7) outcome extraction (von Mises stress, displacement, construct stiffness, micromotion metrics, etc.). This systematic scoping review followed JBI methodology and PRISMA-ScR guidelines to identify FE studies from PubMed, Web of Science, Scopus, and IEEE Xplore. Methodological quality was evaluated using the MQSSFE instrument for computational orthopaedic models.
Results
Twenty-three studies were included, predominantly using single-subject CT models with artificially created Sanders type II–III intra-articular fractures. Most employed calcaneus-only geometries, linear elastic isotropic bone properties, tetrahedral meshes, and quasi-static stance loading. Locking plates, hybrid plate–screw constructs, screw-only MIF, and intramedullary nails were compared via stress distribution and construct stiffness. Several studies introduced topology-optimized plates and micromotion-based fracture gap metrics, demonstrating that MIF with supplementary percutaneous screws can achieve biomechanical stability comparable to ORIF. However, verification (mesh convergence) and validation procedures were inconsistently reported, dynamic loading and multi-patient cohorts were rare, and interfragmentary strain–based healing criteria were largely absent. This delineation of the current technical design space highlights priorities for more physiologically realistic and methodologically robust in silico studies.