热中子对小鼠细胞内源性逆转录病毒的激活作用。

International journal of radiation biology and related studies in physics, chemistry, and medicine Pub Date : 1987-12-01 DOI:10.1080/09553008714552521

O Niwa, T Saigusa, T Ikushima, T Sugahara

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引用次数: 2

摘要

研究了热中子对小鼠成纤维细胞系诱导小鼠内源性病毒的影响。热中子在诱导内源性病毒和杀死细胞方面比x射线更有效。然而，当测量细胞杀伤功能时，两种辐射具有相似的诱导效率。仅热中子的rbe是在假设污染伽马射线的贡献是可加性的情况下计算的。杀毒效果为4.2，病毒诱导效果为4-5。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Activation of endogeneous retroviruses in mouse cells by thermal neutrons.

The effect of thermal neutrons on the induction of murine endogenous viruses from a mouse fibroblast cell line was investigated. Thermal neutrons were more effective than X-rays in induction of endogenous virus as well as in killing of the cells. However, when measured as a function of cell killing, both radiations had similar efficiency of induction. The RBEs of thermal neutrons alone were calculated on the assumption that the contribution of contaminating gamma-rays was additive. It was 4.2 for the killing effect and 4-5 for virus induction.

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International journal of radiation biology and related studies in physics, chemistry, and medicine

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