1型单纯疱疹病毒复发时自然杀伤细胞毒性受损。

Cancer detection and prevention. Supplement : official publication of the International Society for Preventive Oncology, Inc Pub Date : 1987-01-01

Y C Kuo, C Y Lin, S F Cheng, C C Lin, W T Liu

{"title":"1型单纯疱疹病毒复发时自然杀伤细胞毒性受损。","authors":"Y C Kuo, C Y Lin, S F Cheng, C C Lin, W T Liu","doi":"","DOIUrl":null,"url":null,"abstract":"We investigated natural killer (NK) cytotoxicity in patients with recurrent herpes infection by using K562 cells infected with Herpes simplex virus type 1 (HSV-1) as target. The NK cytotoxicity was lower than during convalescence and in controls during recrudescence (0 to 3 days postonset of clinical symptoms; P less than 0.001). In the convalescent phase (4 to 14 days postonset of symptoms) the NK cytotoxicity was significantly higher than in controls (P less than 0.05). These results suggest that low NK cytotoxicity is related to the recurrence of herpes.","PeriodicalId":77685,"journal":{"name":"Cancer detection and prevention. Supplement : official publication of the International Society for Preventive Oncology, Inc","volume":"1 ","pages":"51-5"},"PeriodicalIF":0.0000,"publicationDate":"1987-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Impaired natural killer cytotoxicity during recrudescence of recurrent herpes simplex virus type 1 infection.\",\"authors\":\"Y C Kuo, C Y Lin, S F Cheng, C C Lin, W T Liu\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We investigated natural killer (NK) cytotoxicity in patients with recurrent herpes infection by using K562 cells infected with Herpes simplex virus type 1 (HSV-1) as target. The NK cytotoxicity was lower than during convalescence and in controls during recrudescence (0 to 3 days postonset of clinical symptoms; P less than 0.001). In the convalescent phase (4 to 14 days postonset of symptoms) the NK cytotoxicity was significantly higher than in controls (P less than 0.05). These results suggest that low NK cytotoxicity is related to the recurrence of herpes.\",\"PeriodicalId\":77685,\"journal\":{\"name\":\"Cancer detection and prevention. Supplement : official publication of the International Society for Preventive Oncology, Inc\",\"volume\":\"1 \",\"pages\":\"51-5\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1987-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cancer detection and prevention. Supplement : official publication of the International Society for Preventive Oncology, Inc\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cancer detection and prevention. Supplement : official publication of the International Society for Preventive Oncology, Inc","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

以单纯疱疹病毒1型(HSV-1)感染的K562细胞为靶点，研究自然杀伤(NK)细胞毒性对复发性疱疹感染患者的影响。复发期间(临床症状出现后0 ~ 3天)NK细胞毒性低于恢复期和对照组;P < 0.001)。恢复期(症状出现后4 ~ 14 d) NK细胞毒性显著高于对照组(P < 0.05)。提示低NK细胞毒性与疱疹的复发有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

本刊更多论文

Impaired natural killer cytotoxicity during recrudescence of recurrent herpes simplex virus type 1 infection.

We investigated natural killer (NK) cytotoxicity in patients with recurrent herpes infection by using K562 cells infected with Herpes simplex virus type 1 (HSV-1) as target. The NK cytotoxicity was lower than during convalescence and in controls during recrudescence (0 to 3 days postonset of clinical symptoms; P less than 0.001). In the convalescent phase (4 to 14 days postonset of symptoms) the NK cytotoxicity was significantly higher than in controls (P less than 0.05). These results suggest that low NK cytotoxicity is related to the recurrence of herpes.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Cancer detection and prevention. Supplement : official publication of the International Society for Preventive Oncology, Inc

自引率

0.00%

发文量