青光眼低光照下视力相关困难与视野的关系。

IF 3.3 Q1 OPHTHALMOLOGY

Ophthalmology. Glaucoma Pub Date : 2026-07-01 Epub Date: 2026-01-14 DOI:10.1016/j.ogla.2026.01.006

Maanasi Mahalingam MOptom, Jason Charng PhD, Vanessa T.S. Tang PhD, William H. Morgan MBBS, PhD, Geoffrey Chan MBBS (Hons), MMedSc, Andrew Turpin PhD, Allison M. McKendrick PhD

{"title":"青光眼低光照下视力相关困难与视野的关系。","authors":"Maanasi Mahalingam MOptom, Jason Charng PhD, Vanessa T.S. Tang PhD, William H. Morgan MBBS, PhD, Geoffrey Chan MBBS (Hons), MMedSc, Andrew Turpin PhD, Allison M. McKendrick PhD","doi":"10.1016/j.ogla.2026.01.006","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective or Purpose</h3><div>To determine whether self-reported visual challenges in low lighting are associated with binocular severity of 24-2 visual field (VF) loss in people with glaucoma.</div></div><div><h3>Design</h3><div>A cross-sectional study.</div></div><div><h3>Participants</h3><div>Data from 128 participants with primary open-angle glaucoma enrolled in the longitudinal cohort “Individualised Perimetry Progression Observations in Glaucoma Study” at Lions Eye Institute, Perth, Australia, were analyzed.</div></div><div><h3>Methods</h3><div>Monocular VFs were merged to form an integrated visual field (IVF) using the “best location method.” Visual field locations were divided into four regions: central, peripheral, superior, and inferior. The Low Luminance Questionnaire (LLQ) and Glaucoma Quality of Life-15 (GQL-15) were self-administered electronically. The associations between questionnaire scores and VF indices were assessed using linear regression, considering covariates of age, gender, lens status, and best eye visual acuity. Correlations between the composite and subscales of LLQ and GQL-15 were calculated.</div></div><div><h3>Main Outcome Measures</h3><div>Association between self-reported difficulties under low luminance and binocularly IVFs.</div></div><div><h3>Results</h3><div>Visual field indices were associated with log-transformed composite LLQ scores. Piecewise linear regression identified breakpoints at 21.7 decibels (dB) (95% confidence interval [CI]: 18.1–25.3 dB) and –6.3 dB (95% CI: –2.7 to –9.9 dB) for global integrated VF mean sensitivity and total deviation, respectively. Inferior IVF defects were associated with difficulties at low light levels, especially with driving, adjusting for age, gender, lens status, and better eye visual acuity. The composite and subscales of the LLQ and GQL-15 were moderately correlated.</div></div><div><h3>Conclusions</h3><div>Self-reported difficulties at low light levels were partially explained by binocularly IVF status in people with glaucoma. The LLQ identifies difficulties at low light levels, which are not captured by the standard clinical tests.</div></div><div><h3>Financial Disclosure(s)</h3><div>Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.</div></div>","PeriodicalId":19519,"journal":{"name":"Ophthalmology. Glaucoma","volume":"9 4","pages":"Pages 454-463"},"PeriodicalIF":3.3000,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Association between Vision-Related Difficulties in Low Light Levels and Visual Fields in Glaucoma\",\"authors\":\"Maanasi Mahalingam MOptom, Jason Charng PhD, Vanessa T.S. Tang PhD, William H. Morgan MBBS, PhD, Geoffrey Chan MBBS (Hons), MMedSc, Andrew Turpin PhD, Allison M. McKendrick PhD\",\"doi\":\"10.1016/j.ogla.2026.01.006\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective or Purpose</h3><div>To determine whether self-reported visual challenges in low lighting are associated with binocular severity of 24-2 visual field (VF) loss in people with glaucoma.</div></div><div><h3>Design</h3><div>A cross-sectional study.</div></div><div><h3>Participants</h3><div>Data from 128 participants with primary open-angle glaucoma enrolled in the longitudinal cohort “Individualised Perimetry Progression Observations in Glaucoma Study” at Lions Eye Institute, Perth, Australia, were analyzed.</div></div><div><h3>Methods</h3><div>Monocular VFs were merged to form an integrated visual field (IVF) using the “best location method.” Visual field locations were divided into four regions: central, peripheral, superior, and inferior. The Low Luminance Questionnaire (LLQ) and Glaucoma Quality of Life-15 (GQL-15) were self-administered electronically. The associations between questionnaire scores and VF indices were assessed using linear regression, considering covariates of age, gender, lens status, and best eye visual acuity. Correlations between the composite and subscales of LLQ and GQL-15 were calculated.</div></div><div><h3>Main Outcome Measures</h3><div>Association between self-reported difficulties under low luminance and binocularly IVFs.</div></div><div><h3>Results</h3><div>Visual field indices were associated with log-transformed composite LLQ scores. Piecewise linear regression identified breakpoints at 21.7 decibels (dB) (95% confidence interval [CI]: 18.1–25.3 dB) and –6.3 dB (95% CI: –2.7 to –9.9 dB) for global integrated VF mean sensitivity and total deviation, respectively. Inferior IVF defects were associated with difficulties at low light levels, especially with driving, adjusting for age, gender, lens status, and better eye visual acuity. The composite and subscales of the LLQ and GQL-15 were moderately correlated.</div></div><div><h3>Conclusions</h3><div>Self-reported difficulties at low light levels were partially explained by binocularly IVF status in people with glaucoma. The LLQ identifies difficulties at low light levels, which are not captured by the standard clinical tests.</div></div><div><h3>Financial Disclosure(s)</h3><div>Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.</div></div>\",\"PeriodicalId\":19519,\"journal\":{\"name\":\"Ophthalmology. Glaucoma\",\"volume\":\"9 4\",\"pages\":\"Pages 454-463\"},\"PeriodicalIF\":3.3000,\"publicationDate\":\"2026-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Ophthalmology. Glaucoma\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2589419626000062\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2026/1/14 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q1\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ophthalmology. Glaucoma","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2589419626000062","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/1/14 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

目的或目的：确定低光照下自我报告的视力障碍是否与青光眼患者双眼24-2视野丧失的严重程度有关。设计：横断面研究参与者：来自128名原发性开角型青光眼（POAG）参与者的数据被纳入澳大利亚珀斯狮子眼科研究所的纵向队列“青光眼个体化视野进展观察研究”。方法：采用“最佳定位法”将单眼视野合并形成综合视野。视野位置分为中央、周边、上、下四个区域。低亮度问卷（LLQ）和青光眼生活质量15 （GQL-15）自行电子填写。考虑年龄、性别、晶状体状态和最佳视敏度等协变量，采用线性回归评估问卷得分与视野指数之间的关系。计算了LLQ和GQL-15的复合尺度和子尺度之间的相关性。主要结果测量：低亮度下自我报告的困难与双眼综合视野之间的关联结果：VF指数与对数转换的综合LLQ评分相关。分段线性回归分别在21.7dB （95%CI: 18.1至25.3 dB）和-6.3 dB （95%CI:-2.7至- 99.db）确定了全球综合VF平均灵敏度和TD的断点。较差的IVF缺陷与低光照条件下的困难有关，尤其是驾驶困难、年龄、性别、晶状体状态调整和更好的眼VA。LLQ和GQL-15的复合量表和亚量表具有中等相关性。结论：青光眼患者自述的低光照困难部分解释了双眼综合视野状况。LLQ识别在低光照水平下的困难，这是标准临床测试无法捕捉到的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Association between Vision-Related Difficulties in Low Light Levels and Visual Fields in Glaucoma

Objective or Purpose

To determine whether self-reported visual challenges in low lighting are associated with binocular severity of 24-2 visual field (VF) loss in people with glaucoma.

Design

A cross-sectional study.

Participants

Data from 128 participants with primary open-angle glaucoma enrolled in the longitudinal cohort “Individualised Perimetry Progression Observations in Glaucoma Study” at Lions Eye Institute, Perth, Australia, were analyzed.

Methods

Monocular VFs were merged to form an integrated visual field (IVF) using the “best location method.” Visual field locations were divided into four regions: central, peripheral, superior, and inferior. The Low Luminance Questionnaire (LLQ) and Glaucoma Quality of Life-15 (GQL-15) were self-administered electronically. The associations between questionnaire scores and VF indices were assessed using linear regression, considering covariates of age, gender, lens status, and best eye visual acuity. Correlations between the composite and subscales of LLQ and GQL-15 were calculated.

Main Outcome Measures

Association between self-reported difficulties under low luminance and binocularly IVFs.

Results

Visual field indices were associated with log-transformed composite LLQ scores. Piecewise linear regression identified breakpoints at 21.7 decibels (dB) (95% confidence interval [CI]: 18.1–25.3 dB) and –6.3 dB (95% CI: –2.7 to –9.9 dB) for global integrated VF mean sensitivity and total deviation, respectively. Inferior IVF defects were associated with difficulties at low light levels, especially with driving, adjusting for age, gender, lens status, and better eye visual acuity. The composite and subscales of the LLQ and GQL-15 were moderately correlated.

Conclusions

Self-reported difficulties at low light levels were partially explained by binocularly IVF status in people with glaucoma. The LLQ identifies difficulties at low light levels, which are not captured by the standard clinical tests.