Audrey Brecher, Alicia Vagnozzi, Louis P Dehner, Mai He
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Introduction: Placental teratomas are benign germ cell tumors composed of mature tissues from multiple germ layers. They may mimic a cardiac fetus but lack organized fetal structures and an umbilical cord.
Case presentation: A 25-year-old G5P1224 woman delivered at 34 weeks of gestation following PPROM. Examination of the placenta revealed a 3.5 cm intraplacental, mixed solid and cystic lesion without a pedicle. Histology showed mature tissues including cartilage, ganglion cells, choroid plexus, and ciliated epithelium, consistent with a mature cystic teratoma.
Discussion: The absence of an umbilical cord and embryonic organization distinguishes a mature cystic teratoma from an acardiac twin. Unlike the TRAP sequence, placental teratomas occur in singleton pregnancies, carry no recurrence risk, and pose no threat to fetal or maternal health. Accurate diagnosis is crucial to avoid misclassification and unnecessary intervention.
期刊介绍：
Fetal and Pediatric Pathology is an established bimonthly international journal that publishes data on diseases of the developing embryo, newborns, children, and adolescents. The journal publishes original and review articles and reportable case reports.
The expanded scope of the journal encompasses molecular basis of genetic disorders; molecular basis of diseases that lead to implantation failures; molecular basis of abnormal placentation; placentology and molecular basis of habitual abortion; intrauterine development and molecular basis of embryonic death; pathogenisis and etiologic factors involved in sudden infant death syndrome; the underlying molecular basis, and pathogenesis of diseases that lead to morbidity and mortality in newborns; prenatal, perinatal, and pediatric diseases and molecular basis of diseases of childhood including solid tumors and tumors of the hematopoietic system; and experimental and molecular pathology.
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