[Predictive ability of cognitive reserve in the formation of motor cognitive risk syndrome.]

The cognitive reserve allows the human body to cope with the consequences of diseases and brain injuries. However, the predictive ability of cognitive reserve among patients with brain injuries and visual organ pathology regarding motor-cognitive risk syndrome has not been studied in practice. The aim of the study was to evaluate the prognostic significance of cognitive reserve in the prevalence of motor-cognitive risk syndrome after traumatic brain injury and eye injury and ophthalmopathology in old age. To achieve this goal, three representative groups of patients aged 60-74 years were formed: group 1 - patients with eye injury and ophthalmopathology (n=108), group 2 - patients with traumatic brain injury (n=112), group 3 - patients with combined traumatic brain injury and eye injury and ophthalmopathology (n=105). In all groups of patients, the level of cognitive reserve and the prevalence of motor cognitive risk syndrome were determined in the first three days, 1 month later, 3 months later, and 6 months after injury. Regression method and using the program Statistica 10.0 mathematical models have been developed to predict the prevalence of motor cognitive risk syndrome depending on the level of cognitive reserve. It was found that in the first three days after receiving eye injury and ophthalmopathology, traumatic brain injury and combined traumatic brain injury and eye injury and ophthalmopathology, the level of cognitive reserve was 81,5±2,3; 64,1±1,9 and 60,8±1,5 points, respectively, and the prevalence of motor cognitive risk syndrome during this period was 23,1±1,4; 48,2±2,7 and 58,1±2,3 per 100 subjects, respectively (p<0,01). In subsequent follow-up periods, there was a significant increase in cognitive reserve in the first and second groups, but the prevalence of motor-cognitive risk syndrome significantly decreased only after 3 months among patients with eye injury and ophthalmopathology and with traumatic brain injury and remained high and unchanged among patients with combined traumatic brain injury and eye injury and ophthalmopathology (p>0,05). Regression models have been developed for patients with eye injury and ophthalmopathology, traumatic brain injury, combined traumatic brain injury and eye injury and ophthalmopathology to predict the prevalence of motor cognitive risk syndrome depending on the level of cognitive reserve. Consequently, the level of cognitive reserve makes it possible to predict the formation of motor-cognitive risk syndrome.