三维凝胶中细胞运动表型异质性的检测方法。

Experimental cell biology Pub Date : 1987-01-01 DOI:10.1159/000163423

E D Shields, P B Noble

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引用次数: 7

摘要

使用计算机驱动的三维光学细胞跟踪系统来量化胶原凝胶中Mos-11细胞的运动表型。采用因子分析作为统计手段，使系统产生的复杂变量更易于分析。在54个细胞样本中检测到运动行为的异质性(两种独立的运动表型)。

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Methodology for detection of heterogeneity of cell locomotory phenotypes in three-dimensional gels.

A computer-driven, three-dimensional, optical, cell-tracking system was used to quantify the locomotory phenotypes of Mos-11 cells in a collagen gel. Factor analysis was used as a statistical means to make the complex variables generated by the system more tractable to analysis. Heterogeneity in locomotory behavior (two independent locomotory phenotypes) was detected among a sample of 54 cells.

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Experimental cell biology

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