Mauricio Rigodanzo Mocha, Whady Hueb, Paulo Cury Rezende, Matheus de Oliveira Laterza Ribeiro, Thiago Luis Scudeler, Eduardo Gomes Lima, José Antonio Franchini Ramires, Roberto Kalil Filho
{"title":"低估支架疗效：未经治疗的动脉事件扭曲了冠状动脉介入治疗的结果。","authors":"Mauricio Rigodanzo Mocha, Whady Hueb, Paulo Cury Rezende, Matheus de Oliveira Laterza Ribeiro, Thiago Luis Scudeler, Eduardo Gomes Lima, José Antonio Franchini Ramires, Roberto Kalil Filho","doi":"10.1002/clc.70229","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>Evaluation of percutaneous coronary intervention (PCI) effectiveness typically focuses on overall coronary events, often overlooking the specific location of these events within the coronary vasculature. This study aimed to evaluate the incidence of coronary events in patients treated with PCI and to investigate the correlation between these events, the location of the event within the treated site, and the type of stent used.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>This study determined the proportion of coronary events occurring after percutaneous coronary intervention (PCI) and investigated the association between these events and the location of the previous treatment site. A retrospective cohort analysis was conducted on patients with stable coronary artery disease (CAD) who underwent PCI using either conventional or drug-eluting stents. Data was obtained from the MASS Clinical Research Unit database. The location of the coronary event was determined by angiography.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Five hundred and sixty two patients were included, with 232 (41.3%) experiencing coronary events. 55.8% of the events occurred at the treated site, while the remaining 44.2% were unrelated to the treated site. Of the events related to the treated site, 54.1% occurred in the conventional stent group and 61.1% in the drug-eluting stent group. No statistically significant association was found between the event in the treated site and the type of stent used (<i>p</i> = 0.363).</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>A significant proportion of coronary events occurred in untreated sites. Our results suggest that isolated evaluation of the treated site may provide a more accurate estimate of the effectiveness of stents.</p>\n </section>\n </div>","PeriodicalId":10201,"journal":{"name":"Clinical Cardiology","volume":"48 12","pages":""},"PeriodicalIF":2.3000,"publicationDate":"2025-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/clc.70229","citationCount":"0","resultStr":"{\"title\":\"Underestimation of Stent Efficacy: Untreated Artery Events Distort Coronary Intervention Outcomes\",\"authors\":\"Mauricio Rigodanzo Mocha, Whady Hueb, Paulo Cury Rezende, Matheus de Oliveira Laterza Ribeiro, Thiago Luis Scudeler, Eduardo Gomes Lima, José Antonio Franchini Ramires, Roberto Kalil Filho\",\"doi\":\"10.1002/clc.70229\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Background</h3>\\n \\n <p>Evaluation of percutaneous coronary intervention (PCI) effectiveness typically focuses on overall coronary events, often overlooking the specific location of these events within the coronary vasculature. This study aimed to evaluate the incidence of coronary events in patients treated with PCI and to investigate the correlation between these events, the location of the event within the treated site, and the type of stent used.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>This study determined the proportion of coronary events occurring after percutaneous coronary intervention (PCI) and investigated the association between these events and the location of the previous treatment site. A retrospective cohort analysis was conducted on patients with stable coronary artery disease (CAD) who underwent PCI using either conventional or drug-eluting stents. Data was obtained from the MASS Clinical Research Unit database. The location of the coronary event was determined by angiography.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>Five hundred and sixty two patients were included, with 232 (41.3%) experiencing coronary events. 55.8% of the events occurred at the treated site, while the remaining 44.2% were unrelated to the treated site. Of the events related to the treated site, 54.1% occurred in the conventional stent group and 61.1% in the drug-eluting stent group. No statistically significant association was found between the event in the treated site and the type of stent used (<i>p</i> = 0.363).</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusions</h3>\\n \\n <p>A significant proportion of coronary events occurred in untreated sites. Our results suggest that isolated evaluation of the treated site may provide a more accurate estimate of the effectiveness of stents.</p>\\n </section>\\n </div>\",\"PeriodicalId\":10201,\"journal\":{\"name\":\"Clinical Cardiology\",\"volume\":\"48 12\",\"pages\":\"\"},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2025-12-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/clc.70229\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Cardiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/clc.70229\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Cardiology","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/clc.70229","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
Evaluation of percutaneous coronary intervention (PCI) effectiveness typically focuses on overall coronary events, often overlooking the specific location of these events within the coronary vasculature. This study aimed to evaluate the incidence of coronary events in patients treated with PCI and to investigate the correlation between these events, the location of the event within the treated site, and the type of stent used.
Methods
This study determined the proportion of coronary events occurring after percutaneous coronary intervention (PCI) and investigated the association between these events and the location of the previous treatment site. A retrospective cohort analysis was conducted on patients with stable coronary artery disease (CAD) who underwent PCI using either conventional or drug-eluting stents. Data was obtained from the MASS Clinical Research Unit database. The location of the coronary event was determined by angiography.
Results
Five hundred and sixty two patients were included, with 232 (41.3%) experiencing coronary events. 55.8% of the events occurred at the treated site, while the remaining 44.2% were unrelated to the treated site. Of the events related to the treated site, 54.1% occurred in the conventional stent group and 61.1% in the drug-eluting stent group. No statistically significant association was found between the event in the treated site and the type of stent used (p = 0.363).
Conclusions
A significant proportion of coronary events occurred in untreated sites. Our results suggest that isolated evaluation of the treated site may provide a more accurate estimate of the effectiveness of stents.
期刊介绍：
Clinical Cardiology provides a fully Gold Open Access forum for the publication of original clinical research, as well as brief reviews of diagnostic and therapeutic issues in cardiovascular medicine and cardiovascular surgery.
The journal includes Clinical Investigations, Reviews, free standing editorials and commentaries, and bonus online-only content.
The journal also publishes supplements, Expert Panel Discussions, sponsored clinical Reviews, Trial Designs, and Quality and Outcomes.
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