D Arampatzis, E Athanasiadis, E Kontopodis, Ι Theodorakopoulos, I Theocharakis, S Kostopoulos, D Glotsos, P Asvestas, A Raptis, Ch Manopoulos, K Moulakakis, J Kakisis, I Kalatzis
{"title":"无监督与深度学习方法在腹主动脉瘤CT图像自动分割中的比较研究:初步结果。","authors":"D Arampatzis, E Athanasiadis, E Kontopodis, Ι Theodorakopoulos, I Theocharakis, S Kostopoulos, D Glotsos, P Asvestas, A Raptis, Ch Manopoulos, K Moulakakis, J Kakisis, I Kalatzis","doi":"10.1007/978-3-032-03394-9_33","DOIUrl":null,"url":null,"abstract":"<p><p>Abdominal aortic aneurysm (AAA) is one of the leading causes of death worldwide. Considering that most AAAs remain asymptomatic until they are close to rupture, an efficient workflow for the accurate detection and delineation is crucial for the clinical outcome. In this study, we conduct a comparative analysis of two different AAA segmentation algorithms using X-ray Computed Tomography (CT) images from 18 patients diagnosed with AAA, which have not been used in similar studies before. The methodologies employed include an in-house segmentation algorithm based on conventional image analysis techniques, and a deep learning approach based on the nnU-Net -framework called TotalSegmentor. The CT dataset, which contained baseline studies, was processed, and the manual annotations by clinicians were used as ground truth. Results demonstrated a high degree of accuracy and robustness, with TotalSegmentor achieving an average Sorensen-Dice coefficient of 0.89 and Jaccard index of 0.81 across the dataset, compared to the proposed unsupervised method's scores of 0.85 and 0.77, respectively. These findings highlight the potential of deep learning-based models to enhance clinical workflows, ultimately improving early detection and monitoring of AAA.</p>","PeriodicalId":7270,"journal":{"name":"Advances in experimental medicine and biology","volume":"1489 ","pages":"335-345"},"PeriodicalIF":0.0000,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A Comparative Study of Unsupervised and Deep Learning Methods for Automatic Segmentation of Abdominal Aortic Aneurysm on CT Images: Preliminary Results.\",\"authors\":\"D Arampatzis, E Athanasiadis, E Kontopodis, Ι Theodorakopoulos, I Theocharakis, S Kostopoulos, D Glotsos, P Asvestas, A Raptis, Ch Manopoulos, K Moulakakis, J Kakisis, I Kalatzis\",\"doi\":\"10.1007/978-3-032-03394-9_33\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Abdominal aortic aneurysm (AAA) is one of the leading causes of death worldwide. Considering that most AAAs remain asymptomatic until they are close to rupture, an efficient workflow for the accurate detection and delineation is crucial for the clinical outcome. In this study, we conduct a comparative analysis of two different AAA segmentation algorithms using X-ray Computed Tomography (CT) images from 18 patients diagnosed with AAA, which have not been used in similar studies before. The methodologies employed include an in-house segmentation algorithm based on conventional image analysis techniques, and a deep learning approach based on the nnU-Net -framework called TotalSegmentor. The CT dataset, which contained baseline studies, was processed, and the manual annotations by clinicians were used as ground truth. Results demonstrated a high degree of accuracy and robustness, with TotalSegmentor achieving an average Sorensen-Dice coefficient of 0.89 and Jaccard index of 0.81 across the dataset, compared to the proposed unsupervised method's scores of 0.85 and 0.77, respectively. These findings highlight the potential of deep learning-based models to enhance clinical workflows, ultimately improving early detection and monitoring of AAA.</p>\",\"PeriodicalId\":7270,\"journal\":{\"name\":\"Advances in experimental medicine and biology\",\"volume\":\"1489 \",\"pages\":\"335-345\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2026-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advances in experimental medicine and biology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/978-3-032-03394-9_33\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"Biochemistry, Genetics and Molecular Biology\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in experimental medicine and biology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/978-3-032-03394-9_33","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Biochemistry, Genetics and Molecular Biology","Score":null,"Total":0}
A Comparative Study of Unsupervised and Deep Learning Methods for Automatic Segmentation of Abdominal Aortic Aneurysm on CT Images: Preliminary Results.
Abdominal aortic aneurysm (AAA) is one of the leading causes of death worldwide. Considering that most AAAs remain asymptomatic until they are close to rupture, an efficient workflow for the accurate detection and delineation is crucial for the clinical outcome. In this study, we conduct a comparative analysis of two different AAA segmentation algorithms using X-ray Computed Tomography (CT) images from 18 patients diagnosed with AAA, which have not been used in similar studies before. The methodologies employed include an in-house segmentation algorithm based on conventional image analysis techniques, and a deep learning approach based on the nnU-Net -framework called TotalSegmentor. The CT dataset, which contained baseline studies, was processed, and the manual annotations by clinicians were used as ground truth. Results demonstrated a high degree of accuracy and robustness, with TotalSegmentor achieving an average Sorensen-Dice coefficient of 0.89 and Jaccard index of 0.81 across the dataset, compared to the proposed unsupervised method's scores of 0.85 and 0.77, respectively. These findings highlight the potential of deep learning-based models to enhance clinical workflows, ultimately improving early detection and monitoring of AAA.
期刊介绍:
Advances in Experimental Medicine and Biology provides a platform for scientific contributions in the main disciplines of the biomedicine and the life sciences. This series publishes thematic volumes on contemporary research in the areas of microbiology, immunology, neurosciences, biochemistry, biomedical engineering, genetics, physiology, and cancer research. Covering emerging topics and techniques in basic and clinical science, it brings together clinicians and researchers from various fields.