无监督与深度学习方法在腹主动脉瘤CT图像自动分割中的比较研究:初步结果。

4区 医学 Q2 Biochemistry, Genetics and Molecular Biology
D Arampatzis, E Athanasiadis, E Kontopodis, Ι Theodorakopoulos, I Theocharakis, S Kostopoulos, D Glotsos, P Asvestas, A Raptis, Ch Manopoulos, K Moulakakis, J Kakisis, I Kalatzis
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引用次数: 0

摘要

腹主动脉瘤(AAA)是世界范围内导致死亡的主要原因之一。考虑到大多数aaa在接近破裂时仍无症状,因此准确检测和描绘的高效工作流程对临床结果至关重要。在这项研究中,我们对18名确诊为AAA的患者的x射线计算机断层扫描(CT)图像进行了两种不同的AAA分割算法的比较分析,这两种算法之前没有在类似的研究中使用过。所采用的方法包括基于传统图像分析技术的内部分割算法,以及基于称为TotalSegmentor的nnU-Net框架的深度学习方法。对包含基线研究的CT数据集进行处理,并使用临床医生的手动注释作为基础事实。结果显示了高度的准确性和鲁棒性,TotalSegmentor在数据集上的平均Sorensen-Dice系数为0.89,Jaccard指数为0.81,而提出的无监督方法的得分分别为0.85和0.77。这些发现突出了基于深度学习的模型在增强临床工作流程方面的潜力,最终改善了AAA的早期发现和监测。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Comparative Study of Unsupervised and Deep Learning Methods for Automatic Segmentation of Abdominal Aortic Aneurysm on CT Images: Preliminary Results.

Abdominal aortic aneurysm (AAA) is one of the leading causes of death worldwide. Considering that most AAAs remain asymptomatic until they are close to rupture, an efficient workflow for the accurate detection and delineation is crucial for the clinical outcome. In this study, we conduct a comparative analysis of two different AAA segmentation algorithms using X-ray Computed Tomography (CT) images from 18 patients diagnosed with AAA, which have not been used in similar studies before. The methodologies employed include an in-house segmentation algorithm based on conventional image analysis techniques, and a deep learning approach based on the nnU-Net -framework called TotalSegmentor. The CT dataset, which contained baseline studies, was processed, and the manual annotations by clinicians were used as ground truth. Results demonstrated a high degree of accuracy and robustness, with TotalSegmentor achieving an average Sorensen-Dice coefficient of 0.89 and Jaccard index of 0.81 across the dataset, compared to the proposed unsupervised method's scores of 0.85 and 0.77, respectively. These findings highlight the potential of deep learning-based models to enhance clinical workflows, ultimately improving early detection and monitoring of AAA.

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来源期刊
Advances in experimental medicine and biology
Advances in experimental medicine and biology 医学-医学:研究与实验
CiteScore
5.90
自引率
0.00%
发文量
465
审稿时长
2-4 weeks
期刊介绍: Advances in Experimental Medicine and Biology provides a platform for scientific contributions in the main disciplines of the biomedicine and the life sciences. This series publishes thematic volumes on contemporary research in the areas of microbiology, immunology, neurosciences, biochemistry, biomedical engineering, genetics, physiology, and cancer research. Covering emerging topics and techniques in basic and clinical science, it brings together clinicians and researchers from various fields.
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