东南亚成年人正常体重肥胖的患病率:来自系统回顾和荟萃分析的见解

IF 3.5
Metabolism open Pub Date : 2025-12-01 Epub Date: 2025-11-07 DOI:10.1016/j.metop.2025.100416
K.G. Sruthi , C. Aditya , Paramjot Panda , Jyoti Ranjan Mohanty , Manas Ranjan Behera
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引用次数: 0

摘要

正常体重肥胖(NWO)是指身体质量指数(BMI)正常但体脂率(BF%)升高的个体,使他们患心脏代谢并发症的风险增加。这种情况在东南亚人群中尤为重要,在那里内脏肥胖发生在较低的BMI阈值。然而,区域汇总流行率数据有限。方法系统检索2010年1月~ 2025年5月在PubMed、EMBASE、Scopus、Web of Science、谷歌Scholar等数据库中发表的研究成果。符合条件的研究包括来自东南亚报告NWO患病率的成年人(≥18岁)的观察性数据,其定义为正常BMI (18.5-24.9 kg/m2)和表明过度肥胖的有效替代指标。两位审稿人使用乔安娜布里格斯研究所(JBI)的工具独立进行筛选、数据提取和质量评估。采用Freeman-Tukey双反正弦变换进行随机效应荟萃分析,通过I2统计量评估异质性。结果纳入来自菲律宾、马来西亚、泰国、缅甸、新加坡5个东南亚国家的8项研究,共9028名受试者。NWO的总患病率为57% (95% CI: 37% - 75%),具体研究估计范围为22.8%至82%。异质性高(I2 = 98.9%)。大多数研究使用生物电阻抗分析(BIA)进行体脂评估,并被评为中等至高质量。结论nwo在东南亚成年人中较为常见,以女性和青壮年居多。这些发现强调了BMI作为筛查工具的局限性,并支持将体脂评估纳入公共健康筛查和早期风险检测的临床方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence of normal weight obesity among adults in Southeast Asia: Insights from a systematic review and meta-analysis

Background

Normal Weight Obesity (NWO) describes individuals with a normal body mass index (BMI) but elevated body fat percentage (BF%), placing them at increased risk for cardiometabolic complications. This condition is particularly relevant in Southeast Asian populations, where visceral adiposity occurs at lower BMI thresholds. However, regional pooled prevalence data are limited.

Methods

A systematic search was conducted in PubMed, EMBASE, Scopus, Web of Science, and Google Scholar for studies published between January 2010 and May 2025. Eligible studies included observational data on adults (≥18 years) from Southeast Asia reporting NWO prevalence, defined by normal BMI (18.5–24.9 kg/m2) with validated surrogate indices indicative of excess adiposity. Two reviewers independently conducted screening, data extraction, and quality appraisal using the Joanna Briggs Institute (JBI) tool. A random-effects meta-analysis was performed using the Freeman-Tukey double arcsine transformation, with heterogeneity assessed via the I2 statistic.

Results

Eight studies involving 9028 participants from five Southeast Asian countries (Philippines, Malaysia, Thailand, Myanmar, Singapore) were included. The pooled prevalence of NWO was 57 % (95 % CI: 37 %–75 %), with study-specific estimates ranging from 22.8 % to 82 %. Heterogeneity was high (I2 = 98.9 %). Most studies used bioelectrical impedance analysis (BIA) for body fat assessment and were rated as moderate to high quality.

Conclusion

NWO is common among adults in Southeast Asia, especially in women and young adults. These findings highlight the limitations of BMI as a screening tool and support the integration of body fat assessments into public health screening and clinical protocols for early risk detection.
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来源期刊
Metabolism open
Metabolism open Agricultural and Biological Sciences (General), Endocrinology, Endocrinology, Diabetes and Metabolism
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