{"title":"糖尿病足溃疡患者抑郁发生率及其相关危险因素:荟萃分析和系统回顾","authors":"Yuai Ying, Ying Lv, Hongfang Zhu, Yini Zhang, Xiaowen Fang","doi":"10.1016/j.jtv.2025.100964","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>This study aims to investigate the incidence of depression and its associated risk factors among patients with diabetic foot ulcers (DFU), thereby providing an evidence-based foundation to facilitate early clinical intervention strategies.</div></div><div><h3>Method</h3><div>A comprehensive computerized literature search was conducted to identify studies examining the incidence and/or risk factors of depression among patients with DFU. The retrieved literature was selected according to predefined inclusion and exclusion criteria. Meta-analysis was performed using Stata 18.0 software to assess the incidence of depression among DFU patients.</div></div><div><h3>Results</h3><div>A systematic review of the literature identified 19 eligible studies encompassing a total of 1369 patients. The incidence of depression among patients with DFU was 45 %. The subgroup analysis identified that age, the ulcer duration and Wagner ulcer classification were significant risk factors associated with depressive symptoms among DFU patients (<em>P</em> < 0.05).</div></div><div><h3>Conclusion</h3><div>Depression has a high incidence among DFU patients. Clinical healthcare professionals should implement early, targeted interventions addressing relevant risk factors to mitigate its occurrence.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 4","pages":"Article 100964"},"PeriodicalIF":2.5000,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The incidence of depression and its associated risk factors among diabetic foot ulcers patients: A meta-analysis and systematic review\",\"authors\":\"Yuai Ying, Ying Lv, Hongfang Zhu, Yini Zhang, Xiaowen Fang\",\"doi\":\"10.1016/j.jtv.2025.100964\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><div>This study aims to investigate the incidence of depression and its associated risk factors among patients with diabetic foot ulcers (DFU), thereby providing an evidence-based foundation to facilitate early clinical intervention strategies.</div></div><div><h3>Method</h3><div>A comprehensive computerized literature search was conducted to identify studies examining the incidence and/or risk factors of depression among patients with DFU. The retrieved literature was selected according to predefined inclusion and exclusion criteria. Meta-analysis was performed using Stata 18.0 software to assess the incidence of depression among DFU patients.</div></div><div><h3>Results</h3><div>A systematic review of the literature identified 19 eligible studies encompassing a total of 1369 patients. The incidence of depression among patients with DFU was 45 %. The subgroup analysis identified that age, the ulcer duration and Wagner ulcer classification were significant risk factors associated with depressive symptoms among DFU patients (<em>P</em> < 0.05).</div></div><div><h3>Conclusion</h3><div>Depression has a high incidence among DFU patients. Clinical healthcare professionals should implement early, targeted interventions addressing relevant risk factors to mitigate its occurrence.</div></div>\",\"PeriodicalId\":17392,\"journal\":{\"name\":\"Journal of tissue viability\",\"volume\":\"34 4\",\"pages\":\"Article 100964\"},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2025-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of tissue viability\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0965206X25001123\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/10/25 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"DERMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of tissue viability","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0965206X25001123","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/10/25 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"DERMATOLOGY","Score":null,"Total":0}
The incidence of depression and its associated risk factors among diabetic foot ulcers patients: A meta-analysis and systematic review
Objective
This study aims to investigate the incidence of depression and its associated risk factors among patients with diabetic foot ulcers (DFU), thereby providing an evidence-based foundation to facilitate early clinical intervention strategies.
Method
A comprehensive computerized literature search was conducted to identify studies examining the incidence and/or risk factors of depression among patients with DFU. The retrieved literature was selected according to predefined inclusion and exclusion criteria. Meta-analysis was performed using Stata 18.0 software to assess the incidence of depression among DFU patients.
Results
A systematic review of the literature identified 19 eligible studies encompassing a total of 1369 patients. The incidence of depression among patients with DFU was 45 %. The subgroup analysis identified that age, the ulcer duration and Wagner ulcer classification were significant risk factors associated with depressive symptoms among DFU patients (P < 0.05).
Conclusion
Depression has a high incidence among DFU patients. Clinical healthcare professionals should implement early, targeted interventions addressing relevant risk factors to mitigate its occurrence.
期刊介绍:
The Journal of Tissue Viability is the official publication of the Tissue Viability Society and is a quarterly journal concerned with all aspects of the occurrence and treatment of wounds, ulcers and pressure sores including patient care, pain, nutrition, wound healing, research, prevention, mobility, social problems and management.
The Journal particularly encourages papers covering skin and skin wounds but will consider articles that discuss injury in any tissue. Articles that stress the multi-professional nature of tissue viability are especially welcome. We seek to encourage new authors as well as well-established contributors to the field - one aim of the journal is to enable all participants in tissue viability to share information with colleagues.