当代线圈在经皮冠状动脉介入治疗中的应用:来自多中心COILSEAL注册的见解。

Enrico Cerrato, Giulio Piedimonte, Marco Franzino, Giorgio Marengo, Mario Bollati, Simone Zecchino, David Rutigliano, Francesco Soriano, Massimo Leoncini, Riccardo Mangione, Emanuele Sagazio, Francesco Maiellaro, Francesco Jeva, Gian Paolo Ussia, Fernando Scudiero, Alfonso Franzè, Umberto Barbero, Dario Calderone, Annamaria Nicolino, Fabrizio Ugo, Alessio La Manna, Francesco Costa, Pietro Mazzarotto, Ignacio Jt's Amat-Santos, Ferdinando Varbella
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引用次数: 0

摘要

背景:在经皮冠状动脉介入治疗(PCI)中使用线圈通常是挽救生命和有用的,尽管根据使用说明使用它们的标签外使用。目的:评价PCI合并线圈植入治疗冠状动脉穿孔或关闭冠状动脉瘤/瘘管的住院和远期疗效。方法:在17个欧洲大容量中心进行的245,652例PCI中,最终纳入143例(0.06%)在PCI期间进行线圈植入的患者。收集PCI策略(冠状动脉穿孔时进行盘绕vs.关闭动脉瘤/瘘管)和使用的手术器械。主要结局是技术成功,定义为冠状动脉穿孔或动脉瘤/瘘管的成功密封,程序成功定义为技术成功,无院内主要心血管事件(MACE)。长期MACE和死亡率也有报道。结果:95.7%的病例出现了主要结局,穿孔组和动脉瘤/瘘管组之间无显著差异(94.5%比100%,p = 0.19)。穿孔组手术成功率明显低于穿孔组(83.5% vs. 96.6%, p = 0.01)。在中位随访2年期间,靶病变失败发生率为11.4%,组间无差异。结论:对于治疗冠状动脉穿孔或闭合性动脉瘤/瘘管的患者,在PCI术中置入线圈是安全可行的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Contemporary Use of Coils During Percutaneous Coronary Intervention: Insights From the Multicenter COILSEAL Registry.

Background: Use of coils during percutaneous coronary interventions (PCI) is often life-saving and useful, although their off-label use according to the instructions for use.

Aims: Evaluation of in-hospital and long-term outcomes of patients undergoing PCI with coil implantation for treating coronary perforation or closing coronary artery aneurysms/fistulas.

Methods: Among 245,652 PCIs performed in 17 high-volume European centers, 143 patients (0.06%) undergoing coil implantation during PCI were finally included in the analysis. PCI strategy (coiling performed during coronary perforation vs. closing aneurysm/fistulas) and procedural devices used were collected. The primary outcome was technical success, defined as the successful sealing of coronary perforation or aneurysm/fistulas, and procedural success defined as technical success without in-hospital major cardiovascular events (MACE). Long-term MACE and mortality were also reported.

Results: The primary outcome occurred in 95.7% of cases, with no significant differences observed between the perforation and aneurysm/fistulas groups (94.5% vs. 100%, p = 0.19). Patients in the perforation group had a significantly lower rate of procedural success (83.5% vs. 96.6%, p = 0.01). Target lesion failure occurred in 11.4% of cases without differences between groups at a median follow-up of 2 years.

Conclusions: Coils implantation during PCI is safe and feasible among patients treated for coronary perforations or closing aneurysms/fistulas.

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