Front Cover: Deep Learning for Hyperpolarized NMR of Intrinsically Disordered Proteins Without Resolution Loss: Access to Short-Lived Intermediates

Water down a mill race is a metaphor for our application of deep learning networks to process NMR spectra. The blue water peaks at the top of the waterfall represent the signals obtained through hyperpolarized water. They display high intensity but lack resolution due to the nature of hyperpolarization. The mill wheel, representing the deep learning network, refines the broad water signals. This is illustrated by the intense sharp white peaks visible downstream. More information can be found in the Research Article by D. Kurzbach and co-workers (DOI: 10.1002/chem.202502067).