心血管医学的十字路口：进展和影响的障碍。

IF 38.6 1区医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS

Circulation Pub Date : 2025-10-20 DOI:10.1161/circulationaha.125.075592

Jessica A Regan,Melissa H Laitner,Victor J Dzau

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引用次数: 0

摘要

在过去的75年里，心血管科学技术的进步大大降低了发病率和死亡率。2012年，Nabel和Braunwald博士在《冠状动脉疾病和心肌梗死的故事》中回顾了这一进展，强调了1950年至2010年期间心血管死亡率下降的里程碑式创新。从那时起，药物治疗、介入手术、外科技术和分子医学（包括基因编辑和基于rna的治疗）的突破性发展已经出现。然而，尽管有这些创新，心血管疾病死亡率的改善却停滞不前，这不仅是由于流行病学的变化，也是由于实施过程中持续存在的不公平现象。本文审查了过去15年心血管医学的进展，并提出了一个前瞻性路线图，重点关注预防、负责任的创新和周到的卫生保健服务，以确保技术进步转化为改善所有人的健康结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A Crossroads in Cardiovascular Medicine: Progress and Barriers to Impact.

During the past 75 years, advances in cardiovascular science and technology have significantly reduced morbidity and mortality. In 2012, Drs Nabel and Braunwald reviewed this progress in A Tale of Coronary Artery Disease and Myocardial Infarction, highlighting the landmark innovations that contributed to the decline in cardiovascular death rates from 1950 to 2010. Since then, groundbreaking developments in pharmacologic therapies, interventional procedures, surgical techniques, and molecular medicine-including gene editing and RNA-based treatments-have emerged. However, despite these innovations, improvements in cardiovascular mortality have stalled, driven not only by epidemiologic shifts but also by persistent inequities in implementation. This article examines the past 15 years of progress in cardiovascular medicine and proposes a forward-looking roadmap focused on prevention, responsible innovation, and thoughtful health care delivery to ensure technological advancements translate into improved health outcomes for all.

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来源期刊

Circulation 医学-外周血管病

CiteScore

45.70

自引率

2.10%

发文量

1473

审稿时长

2 months

期刊介绍： Circulation is a platform that publishes a diverse range of content related to cardiovascular health and disease. This includes original research manuscripts, review articles, and other contributions spanning observational studies, clinical trials, epidemiology, health services, outcomes studies, and advancements in basic and translational research. The journal serves as a vital resource for professionals and researchers in the field of cardiovascular health, providing a comprehensive platform for disseminating knowledge and fostering advancements in the understanding and management of cardiovascular issues.