聚（多巴胺）包被铜-槲皮素纳米复合材料的协同化学-光热抗菌活性

IF 4.2 3区工程技术 Q2 CHEMISTRY, APPLIED

Dyes and Pigments Pub Date : 2025-10-16 DOI:10.1016/j.dyepig.2025.113343

Jianing Zhang , Ling Zhang , Ling Zhang , Xianying Cao , Ke Jiang

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引用次数: 0

摘要

开发新型抗菌剂对于对抗耐药性造成的全球健康威胁至关重要。在这里，我们报道了一种多功能纳米复合材料，Cu-Qu-PDA，通过简单的一锅合成制备。该系统协同结合了铜-槲皮素（Cu-Qu）配合物的化学杀菌作用和聚多巴胺（PDA）涂层的强大光热能力。在808 nm近红外（NIR）照射下，纳米复合材料表现出较高的光热转化率（η = 24.45%），并几乎完全根除了金黄色葡萄球菌和大肠杆菌。与单独使用任何一种方法相比，这种化学-光热联合方法显示出更优越的疗效。这项工作强调了一种有前途的多模式策略，可以创建先进的抗菌平台来治疗耐药感染。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Poly(dopamine)-coated copper-quercetin nanocomposite for synergistic chemo-photothermal antibacterial activity

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Poly(dopamine)-coated copper-quercetin nanocomposite for synergistic chemo-photothermal antibacterial activity

Developing novel antibacterial agents is crucial to combat the global health threat posed by drug resistance. Here, we report a multifunctional nanocomposite, Cu-Qu-PDA, prepared through a facile one-pot synthesis. This system synergistically combines the chemical bactericidal action of a copper-quercetin (Cu-Qu) complex with the potent photothermal capabilities of a poly (dopamine) (PDA) coating. Under 808 nm near-infrared (NIR) irradiation, the nanocomposite demonstrated high photothermal conversion (η = 24.45 %) and achieved the near-total eradication of both S. aureus and E. coli. This combined chemo-photothermal approach showed vastly superior efficacy compared to either modality alone. This work highlights a promising multi-modal strategy for creating advanced antibacterial platforms to treat drug-resistant infections.

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来源期刊

Dyes and Pigments 工程技术-材料科学：纺织

CiteScore

8.20

自引率

13.30%

发文量

933

审稿时长

33 days

期刊介绍： Dyes and Pigments covers the scientific and technical aspects of the chemistry and physics of dyes, pigments and their intermediates. Emphasis is placed on the properties of the colouring matters themselves rather than on their applications or the system in which they may be applied. Thus the journal accepts research and review papers on the synthesis of dyes, pigments and intermediates, their physical or chemical properties, e.g. spectroscopic, surface, solution or solid state characteristics, the physical aspects of their preparation, e.g. precipitation, nucleation and growth, crystal formation, liquid crystalline characteristics, their photochemical, ecological or biological properties and the relationship between colour and chemical constitution. However, papers are considered which deal with the more fundamental aspects of colourant application and of the interactions of colourants with substrates or media. The journal will interest a wide variety of workers in a range of disciplines whose work involves dyes, pigments and their intermediates, and provides a platform for investigators with common interests but diverse fields of activity such as cosmetics, reprographics, dye and pigment synthesis, medical research, polymers, etc.