钯催化的1-二茂铁-2-溴苯与炔烃的正[4 + 2]联环反应

IF 2.7 4区化学 Q1 CHEMISTRY, ORGANIC

Asian Journal of Organic Chemistry Pub Date : 2025-10-01 DOI:10.1002/ajoc.202500272

Jiafeng He , Dr. Pei‐Chao Zhang , Yin‐Lin Li , Dr. Wen‐Bo Li , Prof. Dr. Lu Liu

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引用次数: 0

摘要

通过C─C偶联/C─H功能化过程，开发了pd催化的1-二茂铁基-2-溴苯的正式[4 + 2]苯并反应，为各种取代的萘-二茂铁提供了直接途径。该方法为合成多环芳烃（PAHs）提供了一种新颖、高效的方法。初步研究表明，手性膦配体N-Me-PC-Phos在不对称合成平面二茂铁萘衍生物方面具有很大的应用潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Palladium‐Catalyzed Formal [4 + 2] Benzannulation of 1‐ferrocenyl‐2‐bromobenzene with Alkynes

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Palladium‐Catalyzed Formal [4 + 2] Benzannulation of 1‐ferrocenyl‐2‐bromobenzene with Alkynes

A Pd‐catalyzed formal [4 + 2] benzannulation of 1‐ferrocenyl‐2‐bromobenzene with diarylacetylenes involving C─C coupling/C─H functionalization processes are developed, which provides a straightforward access to various substituted naphtho‐ferrocenes. This methodology offers a novel and efficient approach to produce polycyclic aromatic hydrocarbons (PAHs). The preliminary investigation shows the chiral phosphine ligand N‐Me‐PC‐Phos has great potential in the asymmetric synthesis of planar naphtho‐ferrocene derivatives.

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来源期刊

Asian Journal of Organic Chemistry CHEMISTRY, ORGANIC-

CiteScore

4.70

自引率

3.70%

发文量

372

期刊介绍： Organic chemistry is the fundamental science that stands at the heart of chemistry, biology, and materials science. Research in these areas is vigorous and truly international, with three major regions making almost equal contributions: America, Europe and Asia. Asia now has its own top international organic chemistry journal—the Asian Journal of Organic Chemistry (AsianJOC) The AsianJOC is designed to be a top-ranked international research journal and publishes primary research as well as critical secondary information from authors across the world. The journal covers organic chemistry in its entirety. Authors and readers come from academia, the chemical industry, and government laboratories.