基于磁控运动的自拆卸大孔金属-有机框架微电机用于顺序药物释放（Small Methods 10/2025）

IF 9.1 2区材料科学 Q1 CHEMISTRY, PHYSICAL

Small Methods Pub Date : 2025-10-20 DOI:10.1002/smtd.70058

Javier Bujalance Fernández, Víctor de la Asunción-Nadal, Beatriz Jurado Sánchez, Alberto Escarpa

{"title":"基于磁控运动的自拆卸大孔金属-有机框架微电机用于顺序药物释放（Small Methods 10/2025）","authors":"Javier Bujalance Fernández, Víctor de la Asunción-Nadal, Beatriz Jurado Sánchez, Alberto Escarpa","doi":"10.1002/smtd.70058","DOIUrl":null,"url":null,"abstract":"<p><b>Sequential Drug Release</b></p><p>MOF-based magnetic micromotors self-degrade to release two drugs in a controlled and sequential manner at the acidic cancer cells media. The magnetic propulsion of the micromotors facilitates targeted delivery to pre-designated locations, enabling interaction with cancer cells in the culture medium. This approach allows for controlled binding, transport, and membrane rupture toward future in-vivo treatment of tumors. More in article number 2500724, Sánchez, Escarpa, and co-workers.\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":229,"journal":{"name":"Small Methods","volume":"9 10","pages":""},"PeriodicalIF":9.1000,"publicationDate":"2025-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/smtd.70058","citationCount":"0","resultStr":"{\"title\":\"Self-Disassembling Macroporous Metal–Organic Framework-Based Micromotors with Magnetically Controlled Motion for Sequential Drug Release (Small Methods 10/2025)\",\"authors\":\"Javier Bujalance Fernández, Víctor de la Asunción-Nadal, Beatriz Jurado Sánchez, Alberto Escarpa\",\"doi\":\"10.1002/smtd.70058\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><b>Sequential Drug Release</b></p><p>MOF-based magnetic micromotors self-degrade to release two drugs in a controlled and sequential manner at the acidic cancer cells media. The magnetic propulsion of the micromotors facilitates targeted delivery to pre-designated locations, enabling interaction with cancer cells in the culture medium. This approach allows for controlled binding, transport, and membrane rupture toward future in-vivo treatment of tumors. More in article number 2500724, Sánchez, Escarpa, and co-workers.\\n\\n <figure>\\n <div><picture>\\n <source></source></picture><p></p>\\n </div>\\n </figure></p>\",\"PeriodicalId\":229,\"journal\":{\"name\":\"Small Methods\",\"volume\":\"9 10\",\"pages\":\"\"},\"PeriodicalIF\":9.1000,\"publicationDate\":\"2025-10-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/smtd.70058\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Small Methods\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/smtd.70058\",\"RegionNum\":2,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, PHYSICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Small Methods","FirstCategoryId":"88","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/smtd.70058","RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}

引用次数: 0

摘要

顺序释放药物基于emof的磁性微电机自我降解，在酸性癌细胞介质中以可控和顺序的方式释放两种药物。微型马达的磁性推进有助于靶向递送到预先指定的位置，使其能够与培养基中的癌细胞相互作用。这种方法可以控制结合、运输和膜破裂，为未来的肿瘤体内治疗提供可能。更多信息见文章编号2500724，Sánchez， Escarpa和同事。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Self-Disassembling Macroporous Metal–Organic Framework-Based Micromotors with Magnetically Controlled Motion for Sequential Drug Release (Small Methods 10/2025)

查看原文本刊更多论文

Self-Disassembling Macroporous Metal–Organic Framework-Based Micromotors with Magnetically Controlled Motion for Sequential Drug Release (Small Methods 10/2025)

Sequential Drug Release

MOF-based magnetic micromotors self-degrade to release two drugs in a controlled and sequential manner at the acidic cancer cells media. The magnetic propulsion of the micromotors facilitates targeted delivery to pre-designated locations, enabling interaction with cancer cells in the culture medium. This approach allows for controlled binding, transport, and membrane rupture toward future in-vivo treatment of tumors. More in article number 2500724, Sánchez, Escarpa, and co-workers.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Small Methods Materials Science-General Materials Science

CiteScore

17.40

自引率

1.60%

发文量

347

期刊介绍： Small Methods is a multidisciplinary journal that publishes groundbreaking research on methods relevant to nano- and microscale research. It welcomes contributions from the fields of materials science, biomedical science, chemistry, and physics, showcasing the latest advancements in experimental techniques. With a notable 2022 Impact Factor of 12.4 (Journal Citation Reports, Clarivate Analytics, 2023), Small Methods is recognized for its significant impact on the scientific community. The online ISSN for Small Methods is 2366-9608.