以水为氧源的电化学催化苄基C ~ H键直接羟基化/羰基化

IF 2.7 4区化学 Q1 CHEMISTRY, ORGANIC

Asian Journal of Organic Chemistry Pub Date : 2025-10-01 DOI:10.1002/ajoc.202500455

Hui Luo , Yan Wang , Yu He , Zhongjie Wang , Dianjun Li , Jinhui Yang

{"title":"以水为氧源的电化学催化苄基C ~ H键直接羟基化/羰基化","authors":"Hui Luo , Yan Wang , Yu He , Zhongjie Wang , Dianjun Li , Jinhui Yang","doi":"10.1002/ajoc.202500455","DOIUrl":null,"url":null,"abstract":"<div><div>This study proposes an effective method for direct hydroxylation/carbonylation of benzyl C─H bonds. The key feature of this synthesis method is the use of electrochemical conditions that eliminate the need for metal‐free catalyst or oxidants. Water serves as a direct oxygen source to achieve direct hydroxylation/carbonylation of benzyl C─H bonds. The reaction exhibits good selectivity and a broad application range. By controlling the reaction conditions, various types of hydroxylation and carbonylation products can be synthesized, and the feasibility of gram‐scale reactions can be verified.</div></div>","PeriodicalId":130,"journal":{"name":"Asian Journal of Organic Chemistry","volume":"14 10","pages":"Article e00455"},"PeriodicalIF":2.7000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Electrochemically Catalyzed Direct Hydroxylation/Carbonylat‐ion of Benzyl C─H Bonds Using Water as Oxygen Source\",\"authors\":\"Hui Luo , Yan Wang , Yu He , Zhongjie Wang , Dianjun Li , Jinhui Yang\",\"doi\":\"10.1002/ajoc.202500455\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>This study proposes an effective method for direct hydroxylation/carbonylation of benzyl C─H bonds. The key feature of this synthesis method is the use of electrochemical conditions that eliminate the need for metal‐free catalyst or oxidants. Water serves as a direct oxygen source to achieve direct hydroxylation/carbonylation of benzyl C─H bonds. The reaction exhibits good selectivity and a broad application range. By controlling the reaction conditions, various types of hydroxylation and carbonylation products can be synthesized, and the feasibility of gram‐scale reactions can be verified.</div></div>\",\"PeriodicalId\":130,\"journal\":{\"name\":\"Asian Journal of Organic Chemistry\",\"volume\":\"14 10\",\"pages\":\"Article e00455\"},\"PeriodicalIF\":2.7000,\"publicationDate\":\"2025-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Asian Journal of Organic Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://www.sciencedirect.com/org/science/article/pii/S219358072500409X\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, ORGANIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Asian Journal of Organic Chemistry","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/org/science/article/pii/S219358072500409X","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}

引用次数: 0

摘要

本研究提出了一种直接羟化/羰基化苄基C─H键的有效方法。这种合成方法的主要特点是使用电化学条件，消除了对无金属催化剂或氧化剂的需要。水作为直接氧源，实现苄基C─H键的直接羟基化/羰基化。该反应具有良好的选择性，适用范围广。通过控制反应条件，可以合成各种类型的羟基化和羰基化产物，并验证了克级反应的可行性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Electrochemically Catalyzed Direct Hydroxylation/Carbonylat‐ion of Benzyl C─H Bonds Using Water as Oxygen Source

查看原文本刊更多论文

Electrochemically Catalyzed Direct Hydroxylation/Carbonylat‐ion of Benzyl C─H Bonds Using Water as Oxygen Source

This study proposes an effective method for direct hydroxylation/carbonylation of benzyl C─H bonds. The key feature of this synthesis method is the use of electrochemical conditions that eliminate the need for metal‐free catalyst or oxidants. Water serves as a direct oxygen source to achieve direct hydroxylation/carbonylation of benzyl C─H bonds. The reaction exhibits good selectivity and a broad application range. By controlling the reaction conditions, various types of hydroxylation and carbonylation products can be synthesized, and the feasibility of gram‐scale reactions can be verified.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Asian Journal of Organic Chemistry CHEMISTRY, ORGANIC-

CiteScore

4.70

自引率

3.70%

发文量

372

期刊介绍： Organic chemistry is the fundamental science that stands at the heart of chemistry, biology, and materials science. Research in these areas is vigorous and truly international, with three major regions making almost equal contributions: America, Europe and Asia. Asia now has its own top international organic chemistry journal—the Asian Journal of Organic Chemistry (AsianJOC) The AsianJOC is designed to be a top-ranked international research journal and publishes primary research as well as critical secondary information from authors across the world. The journal covers organic chemistry in its entirety. Authors and readers come from academia, the chemical industry, and government laboratories.