结肠直肠癌肝转移的完全细胞减少：不断发展的全身治疗和肝移植。

IF 1.9 3区医学 Q3 ONCOLOGY

Journal of Surgical Oncology Pub Date : 2025-10-16 DOI:10.1002/jso.70112

Viet Le, Jan Franko, Yuman Fong

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引用次数: 0

摘要

约50%-60%的结直肠癌患者发生转移，其中大多数为不可切除的转移性肝病。最近的几项研究强调了全身治疗在将高负担的结直肠癌肝转移（CRLM）患者从不可切除转移到可切除疾病方面的进展，从而提高了中位总生存期。全身治疗的改进和外科手术技术的不断发展，使多学科治疗团队越来越有能力实现CRLM的完全细胞减少，并为越来越多的患者提供长期生存的机会。

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Complete Cytoreduction of Colorectal Liver Metastases: Evolving Systemic Therapy and Liver Transplantation.

Approximately 50%-60% of patients with colorectal cancer develop metastases, of which most have unresectable metastatic liver disease. Several recent studies highlight the progress of systemic therapy in converting patients with high burden of colorectal liver metastases (CRLM) from unresectable to resectable disease, resulting in median overall survival improvements. The improvement of systemic therapy and the evolving spectrum of surgical techniques is allowing multidisciplinary treatment teams an increasing ability to achieve complete cytoreduction of CRLM and offering an increasing number of patients a chance for long-term survival.

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来源期刊

Journal of Surgical Oncology 医学-外科

CiteScore

4.70

自引率

4.00%

发文量

367

审稿时长

2 months

期刊介绍： The Journal of Surgical Oncology offers peer-reviewed, original papers in the field of surgical oncology and broadly related surgical sciences, including reports on experimental and laboratory studies. As an international journal, the editors encourage participation from leading surgeons around the world. The JSO is the representative journal for the World Federation of Surgical Oncology Societies. Publishing 16 issues in 2 volumes each year, the journal accepts Research Articles, in-depth Reviews of timely interest, Letters to the Editor, and invited Editorials. Guest Editors from the JSO Editorial Board oversee multiple special Seminars issues each year. These Seminars include multifaceted Reviews on a particular topic or current issue in surgical oncology, which are invited from experts in the field.