Deep Learning-Based Mpox Skin Lesion Detection and Real-Time Monitoring in a Smart Healthcare System.

Background/Objectives: Mpox, a viral disease marked by distinctive skin lesions, has emerged as a global health concern, underscoring the need for scalable, accessible, and accurate diagnostic tools to strengthen public health responses. This study introduces ITMA'INN, an AI-driven healthcare system designed to detect Mpox from skin lesion images using advanced deep learning. Methods: The system integrates three key components: an AI model pipeline, a cross-platform mobile application, and a real-time public health dashboard. We leveraged transfer learning on publicly available datasets to evaluate pretrained deep learning models. Results: For binary classification (Mpox vs. non-Mpox), Vision Transformer, MobileViT, Transformer-in-Transformer, and VGG16 achieved peak performance, each with 97.8% accuracy and F1-score. For multiclass classification (Mpox, chickenpox, measles, hand-foot-mouth disease, cowpox, and healthy skin), ResNetViT and ViT Hybrid models attained 92% accuracy (F1-scores: 92.24% and 92.19%, respectively). The lightweight MobileViT was deployed in a mobile app that enables users to analyze skin lesions, track symptoms, and locate nearby healthcare centers via GPS. Complementing this, the dashboard equips health authorities with real-time case monitoring, symptom trend analysis, and intervention guidance. Conclusions: By bridging AI diagnostics with mobile technology and real-time analytics, ITMA'INN advances responsive healthcare infrastructure in smart cities, contributing to the future of proactive public health management.