m6A修饰诱导的eIF3-S6动态相分离开关驱动蝗虫换羽（ei）

IF 14.1 1区材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Advanced Science Pub Date : 2025-10-17 DOI:10.1002/advs.71949

Zhihao Hu, Yu Zhou, Huimin Wang, Yaxi Wu, Rui Han, Shili Liu, Feng Jiang, Xiaojiao Guo, Meiling Yang

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引用次数: 0

摘要

蝗虫的蜕皮对昆虫的发育和生长至关重要。迁徙性蝗虫是一种世界性的害虫，在其一生中经历了五个蜕皮阶段，被广泛用作研究蜕皮发育的模型。在他们的研究文章(DOI: 10.1002/advs。202510505)，杨美玲，胡志浩，郭小姣等揭示了m6A修饰EcR和Cht10指导eIF3-S6相分离开关成功脱模的新机制。这张照片显示了一只蝗虫从五龄若虫到成虫的蜕皮过程。图片来源：杨美玲和胡志浩。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Dynamic eIF3-S6 Phase Separation Switch Instructed by m6A Modification Drives the Molting of Locusts (Adv. Sci. 39/2025)

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Dynamic eIF3-S6 Phase Separation Switch Instructed by m6A Modification Drives the Molting of Locusts (Adv. Sci. 39/2025)

Molting of locusts

Molting is critical for insect development and growth. The migratory locust Locusta migratoria, a worldwide pest species, undergoes five molting stages in its life cycle and has been widely used as a model for studying the molting development. In their Research Article (DOI: 10.1002/advs.202510505), Meiling Yang, Zhihao Hu, Xiaojiao Guo, and co-workers reveal a new mechanism in which m⁶A modified EcR and Cht10 instruct a phase separation-switch of eIF3-S6 for successful molting. The photo shows a locust undergoing molting from the fifth-instar nymph to adult stage. lmage credit: Meiling Yang and Zhihao Hu.

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来源期刊

Advanced Science CHEMISTRY, MULTIDISCIPLINARYNANOSCIENCE &-NANOSCIENCE & NANOTECHNOLOGY

CiteScore

18.90

自引率

2.60%

发文量

1602

审稿时长

1.9 months

期刊介绍： Advanced Science is a prestigious open access journal that focuses on interdisciplinary research in materials science, physics, chemistry, medical and life sciences, and engineering. The journal aims to promote cutting-edge research by employing a rigorous and impartial review process. It is committed to presenting research articles with the highest quality production standards, ensuring maximum accessibility of top scientific findings. With its vibrant and innovative publication platform, Advanced Science seeks to revolutionize the dissemination and organization of scientific knowledge.