{"title":"与自制乳制品相关的食源性肉毒杆菌中毒家族群:一个病例系列。","authors":"Khadijeh Saravani, Amirhosein Kamrava, Javad Poursamimi","doi":"10.2147/IMCRJ.S553444","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Foodborne botulism is a life-threatening illness caused by neurotoxins produced by Clostridium botulinum. Although dairy-related cases are rare, they remain a public health concern, especially in regions where traditional food preparation methods are common.</p><p><strong>Case presentation: </strong>This case series describes botulism in three family members-including a pregnant woman-following the consumption of homemade dairy products. All presented with varying degrees of neurological and respiratory symptoms. Two required intubation and intensive care. Laboratory findings confirmed neurotoxin type A in stool and gastric samples. Early administration of a horse-derived trivalent botulinum antitoxin and supportive care resulted in recovery.</p><p><strong>Conclusion: </strong>Prompt recognition and treatment are essential for favorable outcomes. This case series underscores the exceptionally rare occurrence of foodborne botulism linked to homemade dairy products, highlighting the clinical and public health significance of early diagnosis and preventive measures.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"1295-1301"},"PeriodicalIF":0.7000,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12517297/pdf/","citationCount":"0","resultStr":"{\"title\":\"Familial Cluster of Foodborne Botulism Associated with Homemade Dairy Products: A Case Series.\",\"authors\":\"Khadijeh Saravani, Amirhosein Kamrava, Javad Poursamimi\",\"doi\":\"10.2147/IMCRJ.S553444\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Foodborne botulism is a life-threatening illness caused by neurotoxins produced by Clostridium botulinum. Although dairy-related cases are rare, they remain a public health concern, especially in regions where traditional food preparation methods are common.</p><p><strong>Case presentation: </strong>This case series describes botulism in three family members-including a pregnant woman-following the consumption of homemade dairy products. All presented with varying degrees of neurological and respiratory symptoms. Two required intubation and intensive care. Laboratory findings confirmed neurotoxin type A in stool and gastric samples. Early administration of a horse-derived trivalent botulinum antitoxin and supportive care resulted in recovery.</p><p><strong>Conclusion: </strong>Prompt recognition and treatment are essential for favorable outcomes. This case series underscores the exceptionally rare occurrence of foodborne botulism linked to homemade dairy products, highlighting the clinical and public health significance of early diagnosis and preventive measures.</p>\",\"PeriodicalId\":14337,\"journal\":{\"name\":\"International Medical Case Reports Journal\",\"volume\":\"18 \",\"pages\":\"1295-1301\"},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2025-10-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12517297/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Medical Case Reports Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2147/IMCRJ.S553444\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Medical Case Reports Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2147/IMCRJ.S553444","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Familial Cluster of Foodborne Botulism Associated with Homemade Dairy Products: A Case Series.
Background: Foodborne botulism is a life-threatening illness caused by neurotoxins produced by Clostridium botulinum. Although dairy-related cases are rare, they remain a public health concern, especially in regions where traditional food preparation methods are common.
Case presentation: This case series describes botulism in three family members-including a pregnant woman-following the consumption of homemade dairy products. All presented with varying degrees of neurological and respiratory symptoms. Two required intubation and intensive care. Laboratory findings confirmed neurotoxin type A in stool and gastric samples. Early administration of a horse-derived trivalent botulinum antitoxin and supportive care resulted in recovery.
Conclusion: Prompt recognition and treatment are essential for favorable outcomes. This case series underscores the exceptionally rare occurrence of foodborne botulism linked to homemade dairy products, highlighting the clinical and public health significance of early diagnosis and preventive measures.
期刊介绍:
International Medical Case Reports Journal is an international, peer-reviewed, open access, online journal publishing original case reports from all medical specialties. Submissions should not normally exceed 3,000 words or 4 published pages including figures, diagrams and references. As of 1st April 2019, the International Medical Case Reports Journal will no longer consider meta-analyses for publication.