人工智能增强产前护理:一种结合心脏造影和子宫收缩协同作用的双模态胎儿健康评估系统。

IF 3.2 3区 医学 Q2 PHYSIOLOGY
Frontiers in Physiology Pub Date : 2025-09-29 eCollection Date: 2025-01-01 DOI:10.3389/fphys.2025.1638788
Tianxin Qiu, Xinghe Zhou, Jun Zhou, Chunxia Lin, Shiling Jiang, Hui Cheng, Xinhao Wang, Qingshan You
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引用次数: 0

摘要

胎儿心脏监测(FHR)是评估胎儿健康的重要工具,但传统方法依赖于医生的主观解释,表现出显著的可变性,可能导致误诊和过度治疗。人工智能(AI)技术为解决这一问题提供了一种新颖的方法,但现有的研究主要利用单峰(仅fhr)数据,未能符合强调“胎儿心率和子宫收缩(UC)的双峰分析”的临床指南。本研究旨在开发一种基于深度学习的双峰智能监测系统,以提高胎儿健康评估的准确性和临床实用性。方法:研究小组构建了首个中国孕妇胎儿心脏收缩双峰临床数据集(n = 326)。在DenseNet121架构的基础上,引入了选择性注意机制(SK模块),提出了DenseNet121-SK模型。采用图像处理技术提取标准化FHR和UC信号。密集连接和SK模块动态融合了多尺度特征(例如,瞬态波动和收缩周期关联)。该模型在训练过程中采用轻量化设计,以提高医生的可用性。结果:(1)双模态输入显著优于单模态输入,分类AUC为0.944(单模态为0.812),验证了多参数协同解释的临床应用价值;(2) SK模块模拟产科医生的多尺度认知,对异常病例的召回率为100%,准确率为95.88%;(3)该系统有效降低了主观解释的可变性,为减少过度治疗提供了技术支持。讨论:本研究通过轻量级AI设计(仅830万个参数)和双模态数据融合实现了临床可解释性和高性能之间的平衡,使其特别适用于资源有限的初级保健环境。未来的工作应该通过多中心验证进一步优化泛化能力,并探索与大型语言模型的集成以生成标准化报告。这些发现为优化围产期保健资源和人工智能辅助决策提供了重要参考。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
AI-augmented prenatal care: a dual-modal fetal health assessment system integrating cardiotocography and uterine contraction synergy.

Introduction: Fetal heart monitoring (FHR) is a critical tool for assessing fetal health, but traditional methods rely on subjective physician interpretation, exhibiting significant variability that can lead to misdiagnosis and overtreatment. Artificial intelligence (AI) technology offers a novel approach to address this issue, yet existing research predominantly utilizes unimodal (FHR-only) data, failing to align with clinical guidelines emphasizing "bimodality analysis of fetal heart rate and uterine contractions (UC)." This study aims to develop a deep learning-based bimodal intelligent monitoring system to enhance the accuracy and clinical utility of fetal health assessment.

Methods: The research team constructed the first fetal heart-contraction bimodal clinical dataset for Chinese pregnant women (n = 326). Based on the DenseNet121 architecture, a selective attention mechanism (SK module) was introduced, proposing the DenseNet121-SK model. Standardized FHR and UC signals were extracted using image processing techniques. Dense connections and the SK module dynamically fused multi-scale features (e.g., transient fluctuations and contraction cycle associations). The model employed lightweight design during training to enhance physician usability.

Results: (1) Dual-modality input significantly outperformed single-modality input, achieving a classification AUC of 0.944 (vs. 0.812 for single-modality), validating the clinical value of multi-parameter collaborative interpretation; (2) The SK module simulated obstetricians' multi-scale cognition, achieving 95.88% accuracy with 100% recall for abnormal cases; (3) The system effectively reduced subjective interpretation variability, providing technical support for minimizing overtreatment.

Discussion: This study achieves a balance between clinical interpretability and high performance through lightweight AI design (only 8.3 million parameters) and dual-modality data fusion, making it particularly suitable for resource-constrained primary care settings. Future work should further optimize generalization capabilities through multicenter validation and explore integration with large language models to generate standardized reports. These findings provide important references for optimizing perinatal healthcare resources and AI-assisted decision-making.

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来源期刊
CiteScore
6.50
自引率
5.00%
发文量
2608
审稿时长
14 weeks
期刊介绍: Frontiers in Physiology is a leading journal in its field, publishing rigorously peer-reviewed research on the physiology of living systems, from the subcellular and molecular domains to the intact organism, and its interaction with the environment. Field Chief Editor George E. Billman at the Ohio State University Columbus is supported by an outstanding Editorial Board of international researchers. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide.
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