未来50年的正电子发射断层扫描将如何改变我们对慢性疼痛的理解。

IF 5.5 1区医学 Q1 ANESTHESIOLOGY

PAIN® Pub Date : 2025-11-01 DOI:10.1097/j.pain.0000000000003665

Marco L Loggia,Pedro Brugarolas,Ciprian Catana,Jacob M Hooker

{"title":"未来50年的正电子发射断层扫描将如何改变我们对慢性疼痛的理解。","authors":"Marco L Loggia,Pedro Brugarolas,Ciprian Catana,Jacob M Hooker","doi":"10.1097/j.pain.0000000000003665","DOIUrl":null,"url":null,"abstract":"The first modern positron emission tomography (PET) scanner was introduced in 1975-the same year during which the journal PAIN was first published. Over the past 50 years, PET imaging has driven major discoveries in human biology, offering transformative insights into chronic pain. Yet, despite its remarkable versatility, PET remains a relatively underutilized tool in pain research. In this narrative, we explore the vast potential of this imaging technique, envisioning its evolution in the upcoming decades with advancements in scanner technology, novel radioligands, sophisticated data analysis methods, and expanded accessibility. We discuss how these innovations could revolutionize our understanding, diagnosis, and treatment of chronic pain.","PeriodicalId":19921,"journal":{"name":"PAIN®","volume":"16 1","pages":"S71-S74"},"PeriodicalIF":5.5000,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"How the next 50 years of positron emission tomography can transform our understanding of chronic pain.\",\"authors\":\"Marco L Loggia,Pedro Brugarolas,Ciprian Catana,Jacob M Hooker\",\"doi\":\"10.1097/j.pain.0000000000003665\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The first modern positron emission tomography (PET) scanner was introduced in 1975-the same year during which the journal PAIN was first published. Over the past 50 years, PET imaging has driven major discoveries in human biology, offering transformative insights into chronic pain. Yet, despite its remarkable versatility, PET remains a relatively underutilized tool in pain research. In this narrative, we explore the vast potential of this imaging technique, envisioning its evolution in the upcoming decades with advancements in scanner technology, novel radioligands, sophisticated data analysis methods, and expanded accessibility. We discuss how these innovations could revolutionize our understanding, diagnosis, and treatment of chronic pain.\",\"PeriodicalId\":19921,\"journal\":{\"name\":\"PAIN®\",\"volume\":\"16 1\",\"pages\":\"S71-S74\"},\"PeriodicalIF\":5.5000,\"publicationDate\":\"2025-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"PAIN®\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1097/j.pain.0000000000003665\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ANESTHESIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"PAIN®","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/j.pain.0000000000003665","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ANESTHESIOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

第一台现代正电子发射断层扫描（PET）扫描仪于1975年问世，同年《疼痛》杂志首次出版。在过去的50年里，PET成像推动了人类生物学的重大发现，为慢性疼痛提供了变革性的见解。然而，尽管PET具有显著的多功能性，但它在疼痛研究中仍然是一个相对未充分利用的工具。在这篇文章中，我们探讨了这种成像技术的巨大潜力，展望了它在未来几十年里随着扫描仪技术的进步、新型无线电配体、复杂的数据分析方法和扩大的可访问性的发展。我们将讨论这些创新将如何彻底改变我们对慢性疼痛的理解、诊断和治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

How the next 50 years of positron emission tomography can transform our understanding of chronic pain.

The first modern positron emission tomography (PET) scanner was introduced in 1975-the same year during which the journal PAIN was first published. Over the past 50 years, PET imaging has driven major discoveries in human biology, offering transformative insights into chronic pain. Yet, despite its remarkable versatility, PET remains a relatively underutilized tool in pain research. In this narrative, we explore the vast potential of this imaging technique, envisioning its evolution in the upcoming decades with advancements in scanner technology, novel radioligands, sophisticated data analysis methods, and expanded accessibility. We discuss how these innovations could revolutionize our understanding, diagnosis, and treatment of chronic pain.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

PAIN® 医学-临床神经学

CiteScore

12.50

自引率

8.10%

发文量

242

审稿时长

9 months

期刊介绍： PAIN® is the official publication of the International Association for the Study of Pain and publishes original research on the nature,mechanisms and treatment of pain.PAIN® provides a forum for the dissemination of research in the basic and clinical sciences of multidisciplinary interest.