{"title":"代谢组学结合转录组学揭示了薇甘菊不同叶色的形成机制。","authors":"Yuxi Wang, Yumeng Tang, Xi Chen, Xiaodong Yang, Qi Zhou, Yueheng Hu, Xiaohua Meng, Jialin Peng","doi":"10.3389/fpls.2025.1672924","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>The vivid colors of color-leafed plants endow plants with unique ornamental value. At present, there are many researches focusing on the mechanism of flower color formation, while there is less interesting research on color-leafed plants. As an excellent color-leafed plant, <i>Heuchera micrantha</i> has only been studied for its pigment content and physiological characteristics, and the mechanism of color-leafed formation has not been characterized yet.</p><p><strong>Methods: </strong>In this study, we used two varieties of <i>Heuchera micrantha</i> with green and red leaves as materials, and employed a combination of metabolomics and transcriptomics to reveal the molecular mechanisms underlying the formation of different color leaves.</p><p><strong>Results: </strong>Through observation of phenotype, analysis of metabolomics and transcriptomics, and combined analysis of multi-omics, it was found that differential metabolites and differentially expressed genes were enriched in flavonoid metabolism and related pathways. Nine MYB and bHLH transcription-factor candidates implicated in flavonoid metabolism were selected and functionally annotated; five are predicted to act as activators and four as repressors of the flavonoid biosynthetic pathway.</p><p><strong>Discussion: </strong>In summary, this study provides important insights into the coloring mechanism of color-leafed plants and provides gene reserves for subsequent targeted breeding.</p>","PeriodicalId":12632,"journal":{"name":"Frontiers in Plant Science","volume":"16 ","pages":"1672924"},"PeriodicalIF":4.1000,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12511031/pdf/","citationCount":"0","resultStr":"{\"title\":\"Metabolomics combined with transcriptomics reveals the formation mechanism of different leaf colors of <i>Heuchera micrantha</i>.\",\"authors\":\"Yuxi Wang, Yumeng Tang, Xi Chen, Xiaodong Yang, Qi Zhou, Yueheng Hu, Xiaohua Meng, Jialin Peng\",\"doi\":\"10.3389/fpls.2025.1672924\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>The vivid colors of color-leafed plants endow plants with unique ornamental value. At present, there are many researches focusing on the mechanism of flower color formation, while there is less interesting research on color-leafed plants. As an excellent color-leafed plant, <i>Heuchera micrantha</i> has only been studied for its pigment content and physiological characteristics, and the mechanism of color-leafed formation has not been characterized yet.</p><p><strong>Methods: </strong>In this study, we used two varieties of <i>Heuchera micrantha</i> with green and red leaves as materials, and employed a combination of metabolomics and transcriptomics to reveal the molecular mechanisms underlying the formation of different color leaves.</p><p><strong>Results: </strong>Through observation of phenotype, analysis of metabolomics and transcriptomics, and combined analysis of multi-omics, it was found that differential metabolites and differentially expressed genes were enriched in flavonoid metabolism and related pathways. Nine MYB and bHLH transcription-factor candidates implicated in flavonoid metabolism were selected and functionally annotated; five are predicted to act as activators and four as repressors of the flavonoid biosynthetic pathway.</p><p><strong>Discussion: </strong>In summary, this study provides important insights into the coloring mechanism of color-leafed plants and provides gene reserves for subsequent targeted breeding.</p>\",\"PeriodicalId\":12632,\"journal\":{\"name\":\"Frontiers in Plant Science\",\"volume\":\"16 \",\"pages\":\"1672924\"},\"PeriodicalIF\":4.1000,\"publicationDate\":\"2025-09-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12511031/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Frontiers in Plant Science\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.3389/fpls.2025.1672924\",\"RegionNum\":2,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q1\",\"JCRName\":\"PLANT SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in Plant Science","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.3389/fpls.2025.1672924","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"PLANT SCIENCES","Score":null,"Total":0}
Metabolomics combined with transcriptomics reveals the formation mechanism of different leaf colors of Heuchera micrantha.
Introduction: The vivid colors of color-leafed plants endow plants with unique ornamental value. At present, there are many researches focusing on the mechanism of flower color formation, while there is less interesting research on color-leafed plants. As an excellent color-leafed plant, Heuchera micrantha has only been studied for its pigment content and physiological characteristics, and the mechanism of color-leafed formation has not been characterized yet.
Methods: In this study, we used two varieties of Heuchera micrantha with green and red leaves as materials, and employed a combination of metabolomics and transcriptomics to reveal the molecular mechanisms underlying the formation of different color leaves.
Results: Through observation of phenotype, analysis of metabolomics and transcriptomics, and combined analysis of multi-omics, it was found that differential metabolites and differentially expressed genes were enriched in flavonoid metabolism and related pathways. Nine MYB and bHLH transcription-factor candidates implicated in flavonoid metabolism were selected and functionally annotated; five are predicted to act as activators and four as repressors of the flavonoid biosynthetic pathway.
Discussion: In summary, this study provides important insights into the coloring mechanism of color-leafed plants and provides gene reserves for subsequent targeted breeding.
期刊介绍：
In an ever changing world, plant science is of the utmost importance for securing the future well-being of humankind. Plants provide oxygen, food, feed, fibers, and building materials. In addition, they are a diverse source of industrial and pharmaceutical chemicals. Plants are centrally important to the health of ecosystems, and their understanding is critical for learning how to manage and maintain a sustainable biosphere. Plant science is extremely interdisciplinary, reaching from agricultural science to paleobotany, and molecular physiology to ecology. It uses the latest developments in computer science, optics, molecular biology and genomics to address challenges in model systems, agricultural crops, and ecosystems. Plant science research inquires into the form, function, development, diversity, reproduction, evolution and uses of both higher and lower plants and their interactions with other organisms throughout the biosphere. Frontiers in Plant Science welcomes outstanding contributions in any field of plant science from basic to applied research, from organismal to molecular studies, from single plant analysis to studies of populations and whole ecosystems, and from molecular to biophysical to computational approaches.
Frontiers in Plant Science publishes articles on the most outstanding discoveries across a wide research spectrum of Plant Science. The mission of Frontiers in Plant Science is to bring all relevant Plant Science areas together on a single platform.
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