这些报纸背后的人——克谢尼娅·库德里亚绍娃和奥尔加·基尔查诺娃。

IF 3.6 2区生物学 Q1 DEVELOPMENTAL BIOLOGY

Development Pub Date : 2025-10-01 Epub Date: 2025-10-13 DOI:10.1242/dev.205281

{"title":"这些报纸背后的人——克谢尼娅·库德里亚绍娃和奥尔加·基尔查诺娃。","authors":"","doi":"10.1242/dev.205281","DOIUrl":null,"url":null,"abstract":"Hox genes, such as Drosophila Abdominal-B (Abd-B), regulate the morphogenesis of specific anatomical regions along the anteroposterior axis in vertebrates. In their work, Olga Kyrchanova and colleagues find that specific initiator sequences control the activity states of the regulatory domains that direct Abd-B expression in the designated segments during Drosophila development. To know more about their work, we spoke to Ksenia Kudryashova and the corresponding author, Olga Kyrchanova, Group Leader, Institute of Gene Biology, Russian Academy of Sciences, Russia.","PeriodicalId":11375,"journal":{"name":"Development","volume":"152 19","pages":""},"PeriodicalIF":3.6000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The people behind the papers - Ksenia Kudryashova and Olga Kyrchanova.\",\"authors\":\"\",\"doi\":\"10.1242/dev.205281\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Hox genes, such as Drosophila Abdominal-B (Abd-B), regulate the morphogenesis of specific anatomical regions along the anteroposterior axis in vertebrates. In their work, Olga Kyrchanova and colleagues find that specific initiator sequences control the activity states of the regulatory domains that direct Abd-B expression in the designated segments during Drosophila development. To know more about their work, we spoke to Ksenia Kudryashova and the corresponding author, Olga Kyrchanova, Group Leader, Institute of Gene Biology, Russian Academy of Sciences, Russia.\",\"PeriodicalId\":11375,\"journal\":{\"name\":\"Development\",\"volume\":\"152 19\",\"pages\":\"\"},\"PeriodicalIF\":3.6000,\"publicationDate\":\"2025-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Development\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.1242/dev.205281\",\"RegionNum\":2,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/10/13 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q1\",\"JCRName\":\"DEVELOPMENTAL BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Development","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1242/dev.205281","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/10/13 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"DEVELOPMENTAL BIOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

Hox基因，如Drosophila Abdominal-B (Abd-B)，在脊椎动物中调节特定解剖区域的形态发生。在他们的工作中，Olga Kyrchanova及其同事发现，在果蝇发育过程中，特定的启动子序列控制着在指定片段中指导Abd-B表达的调控域的活性状态。为了更多地了解他们的工作，我们采访了Ksenia Kudryashova和通讯作者，俄罗斯科学院基因生物学研究所组长Olga Kyrchanova。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

The people behind the papers - Ksenia Kudryashova and Olga Kyrchanova.

Hox genes, such as Drosophila Abdominal-B (Abd-B), regulate the morphogenesis of specific anatomical regions along the anteroposterior axis in vertebrates. In their work, Olga Kyrchanova and colleagues find that specific initiator sequences control the activity states of the regulatory domains that direct Abd-B expression in the designated segments during Drosophila development. To know more about their work, we spoke to Ksenia Kudryashova and the corresponding author, Olga Kyrchanova, Group Leader, Institute of Gene Biology, Russian Academy of Sciences, Russia.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Development 生物-发育生物学

CiteScore

6.70

自引率

4.30%

发文量

433

审稿时长

3 months

期刊介绍： Development’s scope covers all aspects of plant and animal development, including stem cell biology and regeneration. The single most important criterion for acceptance in Development is scientific excellence. Research papers (articles and reports) should therefore pose and test a significant hypothesis or address a significant question, and should provide novel perspectives that advance our understanding of development. We also encourage submission of papers that use computational methods or mathematical models to obtain significant new insights into developmental biology topics. Manuscripts that are descriptive in nature will be considered only when they lay important groundwork for a field and/or provide novel resources for understanding developmental processes of broad interest to the community. Development includes a Techniques and Resources section for the publication of new methods, datasets, and other types of resources. Papers describing new techniques should include a proof-of-principle demonstration that the technique is valuable to the developmental biology community; they need not include in-depth follow-up analysis. The technique must be described in sufficient detail to be easily replicated by other investigators. Development will also consider protocol-type papers of exceptional interest to the community. We welcome submission of Resource papers, for example those reporting new databases, systems-level datasets, or genetic resources of major value to the developmental biology community. For all papers, the data or resource described must be made available to the community with minimal restrictions upon publication. To aid navigability, Development has dedicated sections of the journal to stem cells & regeneration and to human development. The criteria for acceptance into these sections is identical to those outlined above. Authors and editors are encouraged to nominate appropriate manuscripts for inclusion in one of these sections.