Eric Lopez-Retana, Zoe Gomez-Mendoza, Jaime Guerrero-Quezada, Camila Galvan-Coeto, Maria Tellez-Garcia, Ingrid Luna-Lopez, Luis Hernandez-Zarate, Ricardo Martinez-Tenopala, Carlos Gomez-Nunez, Victor González-Uribe
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Environmental pollutants and allergic sensitization: A systematic literature review.
Background: Exposure to environmental pollutants has been associated with an increased risk of respiratory and allergic diseases.
Objective: To describe the interactions between common pollutants and the immune system and their association with allergic diseases.
Methods: A systematic literature review was conducted using PubMed, Clinical Key, Redalyc, MEDLINE, and SciELO for studies published between 2018 and 2024.
Results: Evidence shows that pollutants such as PM2.5 , PM10 , NO2 , CO, and ozone trigger oxidative stress, inflammatory responses, and epithelial damage, facilitating allergic sensitization, asthma, rhinitis, and dermatitis.
Conclusions: Exposure to environmental pollutants plays a key role in the development and exacerbation of allergic diseases, highlighting the need for preventive measures.
期刊介绍：
The Asian Pacific Journal of Allergy and Immunology (APJAI) is an online open access journal with the recent impact factor (2018) 1.747
APJAI published 4 times per annum (March, June, September, December). Four issues constitute one volume.
APJAI publishes original research articles of basic science, clinical science and reviews on various aspects of allergy and immunology. This journal is an official journal of and published by the Allergy, Asthma and Immunology Association, Thailand.
The scopes include mechanism, pathogenesis, host-pathogen interaction, host-environment interaction, allergic diseases, immune-mediated diseases, epidemiology, diagnosis, treatment and prevention, immunotherapy, and vaccine. All papers are published in English and are refereed to international standards.
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