Xiaoying Yu, Ornella Leukou Nzoutchoum, Daoqi Gao, Christine D Hsu, Thao N Hoang, Yong-Fang Kuo, Abbey B Berenson
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引用次数: 0
摘要
建议感染爱滋病病毒的女性每年接受子宫颈癌筛检,如果连续三次结果正常,间隔时间可延长至每三年一次。由于人乳头瘤病毒感染和子宫颈癌的风险增加,强烈建议终生筛查。我们使用2007-2019年美国医疗保险数据评估了老年FWOH和未感染艾滋病毒的女性(FWOH)的宫颈癌筛查率和宫颈癌/癌前患病率的趋势。我们发现,经年龄调整的宫颈癌筛查率在FWH和FWOH中下降相似(平均年百分比变化:-4.4 [95% CI: -5.2, -3.6] vs. -5.7 [95% CI: -6.8, -4.7], p = 0.11)。然而,经年龄调整的宫颈癌/癌前病变患病率在妇女中呈上升趋势(5.4,[2.9,7.9]),而在妇女中保持稳定(-0.6[-1.4,0.1])。这些发现强调需要严格遵守临床实践指南,在老年妇女中进行宫颈癌筛查。
Cervical cancer screening and prevalence among older US Medicare beneficiaries with and without HIV.
Females with HIV (FWH) are recommended to receive cervical cancer screening annually, with the interval extended to every 3 years after three sequential normal results. Lifelong screening is highly recommended due to their increased risk of human papillomavirus infection and cervical cancer. We assessed the trends in cervical cancer screening rates and cervical cancer/precancer prevalence among older FWH and females without HIV (FWOH) using 2007-2019 US Medicare data. We found that age-adjusted cervical cancer screening rates decreased similarly in both FWH and FWOH (average annual percentage change: -4.4 [95% CI: -5.2, -3.6] vs. -5.7 [95% CI: -6.8, -4.7], p = 0.11). However, the age-adjusted cervical cancer/precancer prevalence showed increasing rates among FWH (5.4, [2.9, 7.9]) while stable in FWOH (-0.6 [-1.4, 0.1]). These findings underscore the need for strict adherence to clinical practice guidelines for cervical cancer screening in older FWH.
期刊介绍:
The International Journal of Cancer (IJC) is the official journal of the Union for International Cancer Control—UICC; it appears twice a month. IJC invites submission of manuscripts under a broad scope of topics relevant to experimental and clinical cancer research and publishes original Research Articles and Short Reports under the following categories:
-Cancer Epidemiology-
Cancer Genetics and Epigenetics-
Infectious Causes of Cancer-
Innovative Tools and Methods-
Molecular Cancer Biology-
Tumor Immunology and Microenvironment-
Tumor Markers and Signatures-
Cancer Therapy and Prevention