Bin Zhang, Fenghai Liu, Guoce Li, Jing Liang, Fan Yang, Li Zhang, Yazhen Zhao, Di Liu, Lan Zhang, Liqing Kang
{"title":"健康汉族成人心脏磁共振衍生房室平面位移的参考范围。","authors":"Bin Zhang, Fenghai Liu, Guoce Li, Jing Liang, Fan Yang, Li Zhang, Yazhen Zhao, Di Liu, Lan Zhang, Liqing Kang","doi":"10.1002/jmri.70146","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Atrioventricular plane displacement (AVPD) and cardiac valve plane displacement (CVPD) are dominant contributors to the longitudinal component of ventricular pump function and vary with age; however, reference values are not available for Han Chinese adults.</p><p><strong>Purpose: </strong>To establish reference ranges for AVPD in healthy Han Chinese adult volunteers using cardiac magnetic resonance (MR).</p><p><strong>Study type: </strong>Prospective, single-center study.</p><p><strong>Population: </strong>Two hundred healthy adult volunteers (45.0 ± 14.5 years; 49.5% male) were recruited between May and July 2024.</p><p><strong>Field strength/sequence: </strong>3.0 Tesla MR imaging; steady-state free precession (SSFP).</p><p><strong>Assessment: </strong>All participants underwent 3.0 Tesla cardiac MR during breath-holding at end-expiration. AVPD for the left ventricle (LVAVPD) and right ventricle (RVAVPD) was quantified using three long-axis cine images with manually inputted points. LVAVPD (average (<sub>avg</sub>), anterior (<sub>ant</sub>), inferior (<sub>inf</sub>), anterior-septal (<sub>ant-sep</sub>), inferior-lateral (<sub>inf-lat</sub>), inferior-septal (<sub>inf-sep</sub>), anterior-lateral (<sub>ant-lat</sub>)), as well as RVAVPD (average (<sub>avg</sub>), right ventricular outflow tract (<sub>rvot</sub>), and lateral (<sub>lat</sub>)), were recorded.</p><p><strong>Statistical tests: </strong>Descriptive statistics; analysis of variance for age groups; multivariate linear regression; significance was set at p < 0.05.</p><p><strong>Results: </strong>Mean values were: LVAVPD<sub>avg</sub>, 14.0 ± 1.5 mm; LVAVPD<sub>ant</sub>, 12.5 ± 1.7 mm; LVAVPD<sub>inf</sub>, 15.7 ± 2.1 mm; LVAVPD<sub>ant-sep</sub>, 12.4 ± 2.0 mm; LVAVPD<sub>inf-lat</sub>, 15.6 ± 2.3 mm; LVAVPD<sub>inf-sep</sub>, 13.0 ± 1.9 mm; LVAVPD<sub>ant-lat</sub>, 14.8 ± 2.0 mm; RVAVPD<sub>avg</sub>, 18.7 ± 2.3 mm; RVAVPD<sub>rvot</sub>, 20.7 ± 3.4 mm; RVAVPD<sub>lat</sub>, 22.6 ± 3.0 mm. No significant sex differences were observed; however, significant differences were noted across the age groups (G<sub><45</sub>, G<sub>45-60</sub>, and G<sub>>60</sub>). Multivariate linear regression analysis identified age, end-diastolic volume (EDV), and end-diastolic volume index (EDVi) as significant independent determinants of AVPD.</p><p><strong>Data conclusion: </strong>This study presents both LVAVPD and RVAVPD reference ranges in healthy Han Chinese adults and demonstrates age-related changes and correlations with EDV, stroke volume (SV), and ejection fraction (EF). These findings support the clinical utility of AVPD in myocardial function assessment.</p><p><strong>Evidence level: </strong>N/A.</p><p><strong>Technical efficacy: </strong>Stage 1.</p>","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":""},"PeriodicalIF":3.5000,"publicationDate":"2025-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Reference Ranges for Cardiac Magnetic Resonance-Derived Atrioventricular Plane Displacement in Healthy Han Chinese Adults.\",\"authors\":\"Bin Zhang, Fenghai Liu, Guoce Li, Jing Liang, Fan Yang, Li Zhang, Yazhen Zhao, Di Liu, Lan Zhang, Liqing Kang\",\"doi\":\"10.1002/jmri.70146\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Atrioventricular plane displacement (AVPD) and cardiac valve plane displacement (CVPD) are dominant contributors to the longitudinal component of ventricular pump function and vary with age; however, reference values are not available for Han Chinese adults.</p><p><strong>Purpose: </strong>To establish reference ranges for AVPD in healthy Han Chinese adult volunteers using cardiac magnetic resonance (MR).</p><p><strong>Study type: </strong>Prospective, single-center study.</p><p><strong>Population: </strong>Two hundred healthy adult volunteers (45.0 ± 14.5 years; 49.5% male) were recruited between May and July 2024.</p><p><strong>Field strength/sequence: </strong>3.0 Tesla MR imaging; steady-state free precession (SSFP).</p><p><strong>Assessment: </strong>All participants underwent 3.0 Tesla cardiac MR during breath-holding at end-expiration. AVPD for the left ventricle (LVAVPD) and right ventricle (RVAVPD) was quantified using three long-axis cine images with manually inputted points. LVAVPD (average (<sub>avg</sub>), anterior (<sub>ant</sub>), inferior (<sub>inf</sub>), anterior-septal (<sub>ant-sep</sub>), inferior-lateral (<sub>inf-lat</sub>), inferior-septal (<sub>inf-sep</sub>), anterior-lateral (<sub>ant-lat</sub>)), as well as RVAVPD (average (<sub>avg</sub>), right ventricular outflow tract (<sub>rvot</sub>), and lateral (<sub>lat</sub>)), were recorded.</p><p><strong>Statistical tests: </strong>Descriptive statistics; analysis of variance for age groups; multivariate linear regression; significance was set at p < 0.05.</p><p><strong>Results: </strong>Mean values were: LVAVPD<sub>avg</sub>, 14.0 ± 1.5 mm; LVAVPD<sub>ant</sub>, 12.5 ± 1.7 mm; LVAVPD<sub>inf</sub>, 15.7 ± 2.1 mm; LVAVPD<sub>ant-sep</sub>, 12.4 ± 2.0 mm; LVAVPD<sub>inf-lat</sub>, 15.6 ± 2.3 mm; LVAVPD<sub>inf-sep</sub>, 13.0 ± 1.9 mm; LVAVPD<sub>ant-lat</sub>, 14.8 ± 2.0 mm; RVAVPD<sub>avg</sub>, 18.7 ± 2.3 mm; RVAVPD<sub>rvot</sub>, 20.7 ± 3.4 mm; RVAVPD<sub>lat</sub>, 22.6 ± 3.0 mm. No significant sex differences were observed; however, significant differences were noted across the age groups (G<sub><45</sub>, G<sub>45-60</sub>, and G<sub>>60</sub>). Multivariate linear regression analysis identified age, end-diastolic volume (EDV), and end-diastolic volume index (EDVi) as significant independent determinants of AVPD.</p><p><strong>Data conclusion: </strong>This study presents both LVAVPD and RVAVPD reference ranges in healthy Han Chinese adults and demonstrates age-related changes and correlations with EDV, stroke volume (SV), and ejection fraction (EF). These findings support the clinical utility of AVPD in myocardial function assessment.</p><p><strong>Evidence level: </strong>N/A.</p><p><strong>Technical efficacy: </strong>Stage 1.</p>\",\"PeriodicalId\":16140,\"journal\":{\"name\":\"Journal of Magnetic Resonance Imaging\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":3.5000,\"publicationDate\":\"2025-10-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Magnetic Resonance Imaging\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1002/jmri.70146\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Magnetic Resonance Imaging","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/jmri.70146","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
Reference Ranges for Cardiac Magnetic Resonance-Derived Atrioventricular Plane Displacement in Healthy Han Chinese Adults.
Background: Atrioventricular plane displacement (AVPD) and cardiac valve plane displacement (CVPD) are dominant contributors to the longitudinal component of ventricular pump function and vary with age; however, reference values are not available for Han Chinese adults.
Purpose: To establish reference ranges for AVPD in healthy Han Chinese adult volunteers using cardiac magnetic resonance (MR).
Study type: Prospective, single-center study.
Population: Two hundred healthy adult volunteers (45.0 ± 14.5 years; 49.5% male) were recruited between May and July 2024.
Field strength/sequence: 3.0 Tesla MR imaging; steady-state free precession (SSFP).
Assessment: All participants underwent 3.0 Tesla cardiac MR during breath-holding at end-expiration. AVPD for the left ventricle (LVAVPD) and right ventricle (RVAVPD) was quantified using three long-axis cine images with manually inputted points. LVAVPD (average (avg), anterior (ant), inferior (inf), anterior-septal (ant-sep), inferior-lateral (inf-lat), inferior-septal (inf-sep), anterior-lateral (ant-lat)), as well as RVAVPD (average (avg), right ventricular outflow tract (rvot), and lateral (lat)), were recorded.
Statistical tests: Descriptive statistics; analysis of variance for age groups; multivariate linear regression; significance was set at p < 0.05.
Results: Mean values were: LVAVPDavg, 14.0 ± 1.5 mm; LVAVPDant, 12.5 ± 1.7 mm; LVAVPDinf, 15.7 ± 2.1 mm; LVAVPDant-sep, 12.4 ± 2.0 mm; LVAVPDinf-lat, 15.6 ± 2.3 mm; LVAVPDinf-sep, 13.0 ± 1.9 mm; LVAVPDant-lat, 14.8 ± 2.0 mm; RVAVPDavg, 18.7 ± 2.3 mm; RVAVPDrvot, 20.7 ± 3.4 mm; RVAVPDlat, 22.6 ± 3.0 mm. No significant sex differences were observed; however, significant differences were noted across the age groups (G<45, G45-60, and G>60). Multivariate linear regression analysis identified age, end-diastolic volume (EDV), and end-diastolic volume index (EDVi) as significant independent determinants of AVPD.
Data conclusion: This study presents both LVAVPD and RVAVPD reference ranges in healthy Han Chinese adults and demonstrates age-related changes and correlations with EDV, stroke volume (SV), and ejection fraction (EF). These findings support the clinical utility of AVPD in myocardial function assessment.
期刊介绍：
The Journal of Magnetic Resonance Imaging (JMRI) is an international journal devoted to the timely publication of basic and clinical research, educational and review articles, and other information related to the diagnostic applications of magnetic resonance.
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