生物医学中的创新支架设计:对生物材料集成和3D打印技术的全面回顾,重点是熔丝制造。

IF 5.2 2区 医学 Q1 PHARMACOLOGY & PHARMACY
Aman Kumar, Cheshta, Avinash, Tasaduq Hussain Mir, M Mursaleen, M A Shah
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引用次数: 0

摘要

本文综述了组织工程中熔丝制造(FFF)支架的设计,强调了其作为组织再生支撑结构的重要性。在组织工程中,将细胞或其他材料植入支架以促进组织生长。该研究的重点是如何使用先进的增材制造(AM)技术,如立体光刻(SLA)、选择性激光烧结(SLS)、低温沉积(如数字层处理(DLP))和FFF来制造具有精确机械性能和改进细胞相容性的复杂支架。这些发展对医疗保健行业产生了重大的积极影响,因为3D打印允许定制医疗设备,包括植入物、手术设备和假肢,从而缩短了休养期并提高了治疗效果。本研究探讨了不同生物材料和技术的整合,以提高支架的机械特性和孔隙度,特别关注FFF在生物医学应用中的使用。本文提供了FFF如何用于创建高效的组织工程解决方案的见解,这是改进生物医学研究和应用中支架设计的有用工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Innovative scaffold design in biomedical: a comprehensive review of biomaterial integration and 3D printing techniques with emphasis on fused filament fabrication.

This review study looks at the design of Fused Filament Fabrication (FFF) scaffolds for tissue engineering, emphasizing their significance as supporting structures for tissue regeneration. Scaffolds are seeded with cells or other materials and implanted to promote tissue growth in tissue engineering. The study focuses on how sophisticated scaffolds with precise mechanical properties and improved cell compatibility can be fabricated using advanced additive manufacturing (AM) techniques such stereolithography (SLA), selective laser sintering (SLS), low-temperature deposition like digital layer processing (DLP), and FFF. These developments have a major positive impact on the healthcare industry since 3D printing allows for the customisation of medical devices including implants, surgical equipment, and prosthetics, which lowers recuperation periods and enhances therapeutic results. This research examines the integration of different biomaterials and techniques to enhance the mechanical characteristics and porosity of scaffolds, with a specific focus on the usage of FFF in biomedical applications. This paper offers insights into how FFF can be used to create efficient tissue engineering solutions, which is a useful tool for improving scaffold design in biomedical research and applications.

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来源期刊
CiteScore
10.70
自引率
8.60%
发文量
951
审稿时长
72 days
期刊介绍: The International Journal of Pharmaceutics is the third most cited journal in the "Pharmacy & Pharmacology" category out of 366 journals, being the true home for pharmaceutical scientists concerned with the physical, chemical and biological properties of devices and delivery systems for drugs, vaccines and biologicals, including their design, manufacture and evaluation. This includes evaluation of the properties of drugs, excipients such as surfactants and polymers and novel materials. The journal has special sections on pharmaceutical nanotechnology and personalized medicines, and publishes research papers, reviews, commentaries and letters to the editor as well as special issues.
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