{"title":"食管经口内窥镜肌切开术适应症的演变：食管病理扩展应用综述。","authors":"Yervant Ichkhanian, John M DeWitt","doi":"10.1007/s11894-025-01016-z","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose of review: </strong>Since its introduction in 2010, peroral endoscopic myotomy (POEM) has reshaped the management of esophageal motility disorders. Originally designed for achalasia, it has expanded into a versatile therapeutic option for a range of esophageal conditions. This review summarizes current evidence on the role of esophageal POEM (E-POEM) across diverse pathologies.</p><p><strong>Recent findings: </strong>Emerging data suggest favorable outcomes of E-POEM for non-achalasia disorders, including spastic esophageal disorders, esophagogastric junction outflow obstruction (EGJOO), diverticular disease, revisional therapy, and other rare indications. However, the evidence remains limited, and careful patient selection is essential before offering treatment. E-POEM has progressed from a procedure for classical achalasia to a promising approach for complex and refractory esophageal conditions. Its broader application may be beneficial when performed in appropriately selected patients under expert hands.</p>","PeriodicalId":10776,"journal":{"name":"Current Gastroenterology Reports","volume":"27 1","pages":"66"},"PeriodicalIF":0.0000,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12513901/pdf/","citationCount":"0","resultStr":"{\"title\":\"Evolving Indications of Esophageal Peroral Endoscopic Myotomy (E-POEM): A Review of Expanding Applications in Esophageal Pathologies.\",\"authors\":\"Yervant Ichkhanian, John M DeWitt\",\"doi\":\"10.1007/s11894-025-01016-z\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose of review: </strong>Since its introduction in 2010, peroral endoscopic myotomy (POEM) has reshaped the management of esophageal motility disorders. Originally designed for achalasia, it has expanded into a versatile therapeutic option for a range of esophageal conditions. This review summarizes current evidence on the role of esophageal POEM (E-POEM) across diverse pathologies.</p><p><strong>Recent findings: </strong>Emerging data suggest favorable outcomes of E-POEM for non-achalasia disorders, including spastic esophageal disorders, esophagogastric junction outflow obstruction (EGJOO), diverticular disease, revisional therapy, and other rare indications. However, the evidence remains limited, and careful patient selection is essential before offering treatment. E-POEM has progressed from a procedure for classical achalasia to a promising approach for complex and refractory esophageal conditions. Its broader application may be beneficial when performed in appropriately selected patients under expert hands.</p>\",\"PeriodicalId\":10776,\"journal\":{\"name\":\"Current Gastroenterology Reports\",\"volume\":\"27 1\",\"pages\":\"66\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-10-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12513901/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Gastroenterology Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1007/s11894-025-01016-z\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Gastroenterology Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s11894-025-01016-z","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Medicine","Score":null,"Total":0}
Evolving Indications of Esophageal Peroral Endoscopic Myotomy (E-POEM): A Review of Expanding Applications in Esophageal Pathologies.
Purpose of review: Since its introduction in 2010, peroral endoscopic myotomy (POEM) has reshaped the management of esophageal motility disorders. Originally designed for achalasia, it has expanded into a versatile therapeutic option for a range of esophageal conditions. This review summarizes current evidence on the role of esophageal POEM (E-POEM) across diverse pathologies.
Recent findings: Emerging data suggest favorable outcomes of E-POEM for non-achalasia disorders, including spastic esophageal disorders, esophagogastric junction outflow obstruction (EGJOO), diverticular disease, revisional therapy, and other rare indications. However, the evidence remains limited, and careful patient selection is essential before offering treatment. E-POEM has progressed from a procedure for classical achalasia to a promising approach for complex and refractory esophageal conditions. Its broader application may be beneficial when performed in appropriately selected patients under expert hands.
期刊介绍：
As the field of gastroenterology and hepatology rapidly evolves, the wealth of published literature can be overwhelming. The aim of the journal is to help readers stay abreast of such advances by offering authoritative, systematic reviews by leading experts. We accomplish this aim by appointing Section Editors who invite international experts to contribute review articles that highlight recent developments and important papers published in the past year. Major topics in gastroenterology are covered, including pediatric gastroenterology, neuromuscular disorders, infections, nutrition, and inflammatory bowel disease. These reviews provide clear, insightful summaries of expert perspectives relevant to clinical practice. An Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research. We also provide commentaries from well-known figures in the field.
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