改良全层皮瓣移植后波士顿I型角膜假体植入术在晚期角膜融化患者中的应用。

IF 2.8 3区医学 Q1 OPHTHALMOLOGY

Acta Ophthalmologica Pub Date : 2025-10-10 DOI:10.1111/aos.70003

Ewa Wróblewska-Czajka, Edward Wylęgała

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引用次数: 0

摘要

目的：评价改良的全层角膜移植技术作为治疗波士顿I型角膜假体（KPro）植入术后晚期角膜融化的治疗策略。方法：11例角膜明显融化、>180°KPro暴露的患者行矫正手术。在坏死组织清创后，取与初次移植直径匹配、中心孔径为3mm的供体移植物，经周向减薄并置于KPro光学筒下方。结果：随访6-12个月，所有病例均保持眼球完整。2例复发患者需要重复手术。5例患者视力改善；在其他情况下，由于合并症，它保持稳定或下降。结论：改良全层移植技术是治疗bostoni型KPro术后晚期角膜融化的理想选择。进一步的研究需要更大的队列和更长时间的随访。

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The use of a modified full-thickness graft flap following Boston type I keratoprosthesis implantation in patients with advanced corneal melting.

Purpose: To evaluate a modified full-thickness corneal graft technique as a remedial strategy for advanced corneal melting following Boston type I keratoprosthesis (KPro) implantation.

Methods: Eleven patients with significant corneal melting and >180° KPro exposure underwent corrective surgery. A donor graft, matching the primary transplant diameter and with a 3-mm central aperture, was thinned circumferentially and positioned beneath the KPro optical cylinder after debridement of necrotic tissue.

Results: Over 6-12 months of follow-up, globe integrity was preserved in all cases. Two patients required repeat procedures for recurrence. Visual acuity improved in five patients; in others, it remained stable or declined due to comorbidities.

Conclusion: The modified full-thickness graft technique is a promising alternative for managing advanced corneal melting after Boston type I KPro. Further studies with larger cohorts and longer follow-up are warranted.

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来源期刊

Acta Ophthalmologica 医学-眼科学

CiteScore

7.60

自引率

5.90%

发文量

433

审稿时长

6 months

期刊介绍： Acta Ophthalmologica is published on behalf of the Acta Ophthalmologica Scandinavica Foundation and is the official scientific publication of the following societies: The Danish Ophthalmological Society, The Finnish Ophthalmological Society, The Icelandic Ophthalmological Society, The Norwegian Ophthalmological Society and The Swedish Ophthalmological Society, and also the European Association for Vision and Eye Research (EVER). Acta Ophthalmologica publishes clinical and experimental original articles, reviews, editorials, educational photo essays (Diagnosis and Therapy in Ophthalmology), case reports and case series, letters to the editor and doctoral theses.