{"title":"前列腺癌的诊断、分类及治疗综述","authors":"Greg Shaw, Ricardo Almeida-Magana","doi":"10.1016/j.mpsur.2025.07.016","DOIUrl":null,"url":null,"abstract":"<div><div>Prostate cancer is the most frequently diagnosed malignancy in adult males. It has a multifactorial aetiology and highly variable clinical course which ranges from an indolent disease, suitable for active surveillance, to an aggressive disease requiring multimodal treatment. Early detection is guided by prostate-specific antigen (PSA) testing, imaging, and biopsy, while management of localized disease is based on risk stratification. Advances in systemic therapies have significantly improved survival and quality of life in advanced stages. This article provides an up-to-date overview of the evolving landscape of prostate cancer diagnosis and treatment.</div></div>","PeriodicalId":74889,"journal":{"name":"Surgery (Oxford, Oxfordshire)","volume":"43 10","pages":"Pages 648-656"},"PeriodicalIF":0.0000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Prostate cancer diagnosis, classification and treatment overview\",\"authors\":\"Greg Shaw, Ricardo Almeida-Magana\",\"doi\":\"10.1016/j.mpsur.2025.07.016\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Prostate cancer is the most frequently diagnosed malignancy in adult males. It has a multifactorial aetiology and highly variable clinical course which ranges from an indolent disease, suitable for active surveillance, to an aggressive disease requiring multimodal treatment. Early detection is guided by prostate-specific antigen (PSA) testing, imaging, and biopsy, while management of localized disease is based on risk stratification. Advances in systemic therapies have significantly improved survival and quality of life in advanced stages. This article provides an up-to-date overview of the evolving landscape of prostate cancer diagnosis and treatment.</div></div>\",\"PeriodicalId\":74889,\"journal\":{\"name\":\"Surgery (Oxford, Oxfordshire)\",\"volume\":\"43 10\",\"pages\":\"Pages 648-656\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Surgery (Oxford, Oxfordshire)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0263931925001425\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Surgery (Oxford, Oxfordshire)","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0263931925001425","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Prostate cancer diagnosis, classification and treatment overview
Prostate cancer is the most frequently diagnosed malignancy in adult males. It has a multifactorial aetiology and highly variable clinical course which ranges from an indolent disease, suitable for active surveillance, to an aggressive disease requiring multimodal treatment. Early detection is guided by prostate-specific antigen (PSA) testing, imaging, and biopsy, while management of localized disease is based on risk stratification. Advances in systemic therapies have significantly improved survival and quality of life in advanced stages. This article provides an up-to-date overview of the evolving landscape of prostate cancer diagnosis and treatment.
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