{"title":"健康儿童拉赫氏菌血症首例报告","authors":"Gioele Ballarò , Fabian Spigariol , Yves Fougère","doi":"10.1016/j.clinpr.2025.100515","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div><em>Rahnella</em> species are environmental Gram-negative bacilli rarely reported as human pathogens, typically in immunocompromised individuals or those with chronic medical conditions. We report the first known case of bacteremia caused by <em>Rahnella</em> species in a paediatric patient without comorbidities or identifiable risk factors.</div></div><div><h3>Case Report</h3><div>A previously healthy 4-year-old Swiss girl presented with prolonged fever and abdominal pain without a clear infectious focus. Laboratory tests showed leukocytosis and elevated inflammatory markers.</div></div><div><h3>Results</h3><div>Blood cultures grew <em>Rahnella</em> sp. Empirical treatment with intravenous ceftriaxone, later switched to meropenem due to a mild allergic reaction, led to rapid clinical improvement. The patient completed a 10-day antibiotic course and fully recovered without complications.</div></div><div><h3>Conclusion</h3><div>This case highlights the capacity of <em>Rahnella</em> sp. to act as a true pathogen even in patients without significant comorbidities. Our findings suggest a need to reconsider the clinical relevance of <em>Rahnella</em> sp., which may cause invasive infections in immunocompetent hosts—not just opportunistic disease in vulnerable populations.</div></div>","PeriodicalId":33837,"journal":{"name":"Clinical Infection in Practice","volume":"28 ","pages":"Article 100515"},"PeriodicalIF":0.0000,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"First case report of Rahnella bacteremia in a healthy child\",\"authors\":\"Gioele Ballarò , Fabian Spigariol , Yves Fougère\",\"doi\":\"10.1016/j.clinpr.2025.100515\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div><em>Rahnella</em> species are environmental Gram-negative bacilli rarely reported as human pathogens, typically in immunocompromised individuals or those with chronic medical conditions. We report the first known case of bacteremia caused by <em>Rahnella</em> species in a paediatric patient without comorbidities or identifiable risk factors.</div></div><div><h3>Case Report</h3><div>A previously healthy 4-year-old Swiss girl presented with prolonged fever and abdominal pain without a clear infectious focus. Laboratory tests showed leukocytosis and elevated inflammatory markers.</div></div><div><h3>Results</h3><div>Blood cultures grew <em>Rahnella</em> sp. Empirical treatment with intravenous ceftriaxone, later switched to meropenem due to a mild allergic reaction, led to rapid clinical improvement. The patient completed a 10-day antibiotic course and fully recovered without complications.</div></div><div><h3>Conclusion</h3><div>This case highlights the capacity of <em>Rahnella</em> sp. to act as a true pathogen even in patients without significant comorbidities. Our findings suggest a need to reconsider the clinical relevance of <em>Rahnella</em> sp., which may cause invasive infections in immunocompetent hosts—not just opportunistic disease in vulnerable populations.</div></div>\",\"PeriodicalId\":33837,\"journal\":{\"name\":\"Clinical Infection in Practice\",\"volume\":\"28 \",\"pages\":\"Article 100515\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-10-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Infection in Practice\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2590170225001104\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Infection in Practice","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2590170225001104","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
First case report of Rahnella bacteremia in a healthy child
Background
Rahnella species are environmental Gram-negative bacilli rarely reported as human pathogens, typically in immunocompromised individuals or those with chronic medical conditions. We report the first known case of bacteremia caused by Rahnella species in a paediatric patient without comorbidities or identifiable risk factors.
Case Report
A previously healthy 4-year-old Swiss girl presented with prolonged fever and abdominal pain without a clear infectious focus. Laboratory tests showed leukocytosis and elevated inflammatory markers.
Results
Blood cultures grew Rahnella sp. Empirical treatment with intravenous ceftriaxone, later switched to meropenem due to a mild allergic reaction, led to rapid clinical improvement. The patient completed a 10-day antibiotic course and fully recovered without complications.
Conclusion
This case highlights the capacity of Rahnella sp. to act as a true pathogen even in patients without significant comorbidities. Our findings suggest a need to reconsider the clinical relevance of Rahnella sp., which may cause invasive infections in immunocompetent hosts—not just opportunistic disease in vulnerable populations.